Main description:

The reader will be introduced to various aspects of the fundamentals of nanotechnology based drug delivery systems and the application of these systems for the delivery of small molecules, proteins, peptides, oligonucleotides and genes. How these systems overcome challenges offered by biological barriers to drug absorption and drug targeting will also be described.

Contents:

Fundamentals of Nanotechnology in Drug Delivery.- Physicochemical Principles of Nanosized Drug Delivery Systems.- Block Copolymer Synthesis for Nanoscale Drug and Gene Delivery.- Supercritical Fluid Technology for Nanotechnology in Drug Delivery.- Nanotubes, Nanorods, Nanofibers, and Fullerenes for Nanoscale Drug Delivery.- Drug Loading into and In Vitro Release from Nanosized Drug Delivery Systems.- Nanotechnology-Based Biosensors in Drug Delivery.- Biopharmaceutical, Physiological, and Clinical Considerations for Nanotechnology in Drug Delivery.- Nanomaterials and Biocompatibility: BioMEMS and Dendrimers.- Nanomaterials and Biocompatibility: Carbon Nanotubes and Fullerenes.- Factors Controlling Pharmacokinetics of Intravenously Injected Nanoparticulate Systems.- Controlled Release and Nanotechnology.- Nanotechnology for Intracellular Delivery and Targeting.- Nanotechnology for the Delivery of Small Molecules, Proteins and Nucleic Acids.- Nano-sized Advanced Delivery Systems as Parenteral Formulation Strategies for Hydrophobic Anti-cancer Drugs.- Engineering of Amphiphilic Block Copolymers for Drug and Gene Delivery.- PAMAM Dendrimers as Nanoscale Oral Drug Delivery Systems.- Nanoemulsions for Intravenous Drug Delivery.- Nanotechnology for Cancer Chemotherapy.- Nanotechnology for Cancer Vaccine Delivery.- Stimuli-Sensitive Nanotechnology for Drug Delivery.- A Look to the Future of Nanotechnology in Drug Delivery.- Nanotechnology in Drug Delivery: Past, Present, and Future.- Nanotechnology in Drug Development and Life Cycle Management.- Nanopharmaceuticals: Challenges and Regulatory Perspective.