Main description:

Teaching mechanical and structural biomaterials concepts for successful medical implant design, this self-contained text provides a complete grounding for students and newcomers to the field. Split into three sections: Materials, Mechanics and Case Studies, it begins with a review of sterilization, biocompatibility and foreign body response before presenting the fundamental structures of synthetic biomaterials and natural tissues. Mechanical behavior of materials is then discussed in depth, covering elastic deformation, viscoelasticity and time-dependent behavior, multiaxial loading and complex stress states, yielding and failure theories, and fracture mechanics. The final section on clinical aspects of medical devices provides crucial information on FDA regulatory issues and presents case studies in four key clinical areas: orthopedics, cardiovascular devices, dentistry and soft tissue implants. Each chapter ends with a list of topical questions, making this an ideal course textbook for senior undergraduate and graduate students, and also a self-study tool for engineers, scientists and clinicians.

Contents:

Part I. Materials: 1. Biocompatibility, sterilization and materials selection for implant design; 2. Metals for medical implants; 3. Ceramics; 4. Polymers; 5. Mechanical behavior of structural tissues; Part II. Mechanics: 6. Elasticity; 7. Viscoelasticity; 8. Failure theories; 9. Fracture mechanics; 10. Fatigue; 11. Friction, lubrication and wear; Part III. Case Studies: 12. Regulatory affairs and testing; 13. Orthopedics; 14. Cardiovascular devices; 15. Oral and maxillofacial devices; 16. Soft tissue replacements; Appendix A. Selected topics from mechanics of materials; Appendix B. Table of material properties of engineering biomaterials and tissues; Appendix C. Teaching methodologies in biomaterials; Glossary; List of symbols.