Main description:

A comprehensive review the state-of-the-art in atherosclerosis of the arteries of the legs and feet. The authors discuss in detail the primary symptom-claudication-an intermittent pain in the leg or foot while walking, its predisposing factors, the current diagnostic methodologies, the impressive advances in the therapeutic armamentarium, and the need to screen for co-existing coronary artery disease. Additional chapters describe cutting-edge noninvasive angiography and vascular flow studies, specific drug therapy for claudication, regression of atherosclerosis therapy, gene therapy, and drug eluting stents for peripheral arterial disease. The authors also examine the epidemiology of LEAD, the effects of smoking and effective smoking cessation programs, its pathogenesis and its association with lipid abnormalities and hypertension, aggressive risk factor modification, and the need to measure the ankle brachial index of every patient over 45.

Contents:

Claudication: Clinical Diagnosis and Differential Diagnosis
Dennis G. Caralis

Noninvasive Diagnostic Evaluation of Peripheral Arterial Disease
Nicos Labropoulos and Apostolos K. Tassiopoulos

Smoking and Smoking Cessation
Albert J. Bellg and Aristdis N. Mavridis

Peripheral Arterial Disease and Diabetes
George L. Bakris

Hyperlipidemia in Peripheral Arterial Disease
Ambika Babu, C. R. Kannan, and Theodore Mazzone

Hypertension and Peripheral Vascular Disease
Anjula Gandhi, Jay Garg, and George L. Bakris

Physical Inactivity is a Risk Factor for Lower Extremity Arterial Disease and Coronary Heart Disease
Dennis G. Caralis and Stamatis Dimitropoulos

Pathogenesis of Atherosclerotic Vascular Disease
Bassem Jamil Basha, George L. Bakris, and James R. Sowers

Lower Extremity Arterial Disease Co-Existing With Coronary Artery Disease
Dennis G. Caralis

Medical Therapy of Claudication and Lower Extremity Arterial Disease
Dennis G. Caralis

Exercise Therapy for Lower Extremity Arterial Disease
Peter F. Kokkinos

Endovascular Strategies for Management of Claudication and Lower Extremity Arterial Disease
Michael C. Brunner and Dennis G. Caralis

Severe Lower Extremity Arterial Disease: Limb Salvage and Revascularization
Chad E. Jacobs and Walter J. McCarthy

Index