Surfactant Replacement Therapy
- Edition: Softcover reprint of the original 1st ed. 1988
- Author/s: Lachmann, B.
- Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
- ISBN: 9783642733079
- Format: Paperback
- Pages: 404 pages
- Publication date: 10 December 2011
- Dimensions: 170mm (Width), 244mm (Height), 21mm (Spine width)
- Weight: 693g
This book presents state-of-the-art information from the groups who have developed and used different types of surfactant. The latest advances concerning in vivo and in vitro evaluation of different types of surfactant as well as clinical consequences, such as changes in ventilator settings following surfactant replacement therapy and immunological questions, are discussed. Apart from neonatal RDS, the book also focuses on current experimental and clinical aspects of adult RDS that offer hopeful therapeutic measures for treating this disease. Finally, new results from experimental studies on the "second generation of surfactant preparations", for example, recombinant surfactant (a combination of artificial lipids and surfactant specific human proteins produced with bioengineering methods) are presented. This book will be of value to all physicians and research workers interested in acute respiratory failure in neonates, children and adults.
Contents: Experimental Evaluation of Surfactant for Replacement Therapy.- Diagnostics of Surfactant Deficiency.- Surfactant Replacement in Newborn Infants.- Surfactant Replacement in ARDS and Other Lung Diseases.- What Happens After Surfactant Replacement Therapy?- Prospects for the Future.- Lipid Metabolism and Its Influence by Pharmacological Means.