Nitric oxide (NO) is a gas naturally found in the body that conveys information between cells. In the last decade researchers have found that NO is a signaling molecule of key importance for the cardiovascular system, regulating blood pressure and blood flow to different organs. In addition, discoveries surrounding nitric oxide's role as a principal neurotransmitter moderating erectile function, a pathophysiological negotiator and messenger in inflammation, and a weapon against infections have increased research attention across the fields of biochemistry, chemistry, molecular biology, gene therapy, cell biology, immunology, pharmacology, neuroscience, and physiology. It is edited by Nobel Laureate Louis J. Ignarro. It features up-to-date therapeutic implications of nitric oxide research. It is authored by world experts on nitric oxide. It includes detailed research of the biochemistry and synthesis of nitric oxide.