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MORE ABOUT THIS BOOK
Main description:
An interdisciplinary panel of pioneers and opinion leaders review the basic, preclinical, clinical, and developmental pathways to new treatment strategies, such as therapeutic angiogenesis and myogenesis. The authors take advantage of new biological understanding, novel therapeutic targets, multiple available and well-studied therapeutic strategies, and the necessary imaging techniques to measure outcomes. Their in-depth discussions cover the identification of new therapeutic targets and pathways, the investigation of transcriptional factors, master switch molecules, cell-based approaches, chemokines, a better understanding of the effects of aging, endothelial dysfunction, and hypercholesterolemia in response to angiogenic stimuli. Highlights include examination of drug delivery problems, outcomes measure, stem therapy, high-risk interventions, development pathways, and future possibilities.
Contents:
No-Option Patients: A Growing Problem
Roger J. Laham and Donald S. Baim
Transcriptional Regulation of Angiogenesis
Peter Oettgen
Preclinical Models and Experience to Date
Aysegul Yegin and Nicolas A. Chronos
The Coronary Microcirculation and Angiogenesis
Pierre Voisine, David G. Harrison, and Frank W. Sellke
Local and Regional Vascular Delivery for Therapeutic Angiogenesis and Myogenesis
Erik T. Price, Alan C. Yeung, and Mehrdad Rezaee
Imaging Angiogenesis: A Guide for Clinical Management and Therapeutic Trials
Justin D. Pearlman
Myocardial Angiogenesis: Protein Growth Factors
Kwang Soo Cha, Robert S. Schwartz, and Timothy D. Henry
Gene Therapy for Angiogenesis in the Treatment of Cardiovascular and Peripheral Arterial Disease
Pinak B. Shah, Kapildeo Lotun, and Douglas W. Losordo
Therapeutic Angiogenesis in Peripheral Arterial Disease: Current Approaches and Future Directions
Richard E. Waters and Brian H. Annex
Bone Marrow Cell Transplantation for Myocardial Regeneration and Therapeutic Angiogenesis
Hung-Fat Tse, Pui-Yin Lee, and Chu-Pak Lau
Transplantation of Embryonic Stem Cells for Myocardial Regeneration and Angiogenesis
Yong-Fu Xiao, Jiang-Yong Min, and James P. Morgan
Skeletal Myoblast Transplantation for Cardiac Repair
Audrey Rosinberg, Jamal S. Rana, and Roger J. Laham
Transmyocardial Laser Revascularization
Keith A. Horvath
Index
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: November, 2010
Pages: 372
Weight: 631g
Availability: Available
Subcategories: Cardiovascular Medicine
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