Main description:

This book describes a standardized method for classifying and reporting invasive endometrial malignancies via direct endometrial sampling. Featuring a wealth of color illustrations, it provides specific diagnostic categories and cytomorphologic criteria to promote uniform and reliable diagnoses. It also describes the history of directly sampled endometrial cytology, reviews the sampling techniques and algorithmic approach, discusses specimen adequacy, and outlines challenges for the future. The Yokohama System for Reporting Endometrial Cytology - Definitions, Criteria and Explanatory Notes offers a valuable resource for researchers at clinical cytopathological laboratories around the world whose work involves gynecological cytology, oncology, pathology, and cytopathology. It will also appeal to researchers in the fields of cytotechnology, basic science, pathology and related industries, medical residents and clinicians.

Contents:

1. Endometrial Cytology in Historical Perspective

2. Overview of the Yokohama System for Reporting Endometrial Cytology

3. Pathogenetic Bases of the Yokohama System for Reporting Endometrial Cytology

4. Endometrial Cell Sampling Procedure to Obtain Cytologic Specimens

5. Algorithmic Interpretational and Diagnostic Approach to Endometrial Cytology for the Yokohama System

6. Evaluation of sample Adequacy: Cytologic criteria

7. Processing Methodology of Endometrial Cytology Samples

8. Negative for Malignant Tumors and Precursors: TYS1

9. Endometrial Hyperplasia without Atypia

10. Endometrial Atypical Hyperplasia / Endometrioid Intraepithelial Neoplasia

11. Malignant Neoplasms

12. Endometrial Glandular and Stromal Breakdown (EGBD) as Benign Mimics of Malignancy

13. Atypical Endometrial Cells (ATEC)

14. Cell Block Techniques for Endometrial Cytology Technical Procedures, Role of Immunocytochemistry, Advantages, Applications

15. Molecular Pathology of Endometrial Carcinoma: A general appraisal

16. Molecular Pathology of Endometrial Carcinoma on LBC Samples and Cell Blocks

17. Future Challenges and Perspectives of Endometrial Cytology

18. The Future Direction in Endometrial Oncology Through the Liquid Biopsy