Main description:

This issue of Hematology/Oncology Clinics, edited by Dr. Ali Taher, focuses on Thalassemia. Topics include, but are not limited to, Molecular basis and genetic modifiers; Evolving spectrum of epidemiology; Clinical classification; Ineffective erythropoiesis, anemia and iron overload; Hypercoagulability and vascular disease; Clinical complications and their management; Transfusion and iron chelation therapy; Hematopoietic Stem Cell Transplantation in Thalassemia; Gene therapy and genome editing; Emerging therapies; Quality of life; Advances in understanding pathophysiology and treatment of fertility, pregnancy, and prenatal diagnosis in Thalassemia; and MRI for iron overload.

Contents:

Thalassemia - Table of Contents

Erratum

Preface: Thalassemia

The Evolving Spectrum of the Epidemiology of Thalassemia

Molecular Basis and Genetic Modifiers of Thalassemia

Clinical Classification, Screening, and Diagnosis for Thalassemia

Ineffective Erythropoiesis: Anemia and Iron Overload

Clinical Complications and Their Management

Hypercoagulability and Vascular Disease

Interaction of Transfusion and Iron Chelation in Thalassemias

Iron Chelation Therapy as a Modality of Management

MRI for Iron Overload in Thalassemia

Fertility and Pregnancy in Women with Transfusion-Dependent Thalassemia

Hematopoietic Stem Cell Transplantation in Thalassemia

Gene Therapy and Genome Editing

Emerging Therapies