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Synthetic Methods in Drug Discovery: Volume 2
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Main description:

Building on key reactions presented in Volume 1, Synthetic Methods in Drug Discovery Volume 2 covers a range of important reaction types including organometallic chemistry, fluorination approaches and asymmetric methods as well as new and exciting areas such as Csp2-Csp3 couplings, catalytic amide bond forming reactions, hydrogen borrowing chemistry and methods to access novel motifs and monomers. This book provides both academic and industrial perspectives on key reactions giving the reader an excellent overview of the techniques used in modern synthesis. Reaction types are conveniently framed in the context of their value to industry and the challenges and limitations of methodologies are discussed with relevant illustrative examples. Moreover, key opportunities in expanding chemical space are presented, including the increasingly important syntheses that introduce three-dimensional molecular shape. Edited and authored by leading scientists from both academia and industry, this book will be a valuable reference for all chemists involved in drug discovery as well as postgraduate students in medicinal chemistry.


Contents:

Lithium, Magnesium, and Copper: Contemporary Applications of Organometallic Chemistry in the Pharmaceutical Industry; C-N Bond Formation via Hydrogen Transfer; Synthesis of Sulfonamides; Asymmetric Methods and Their Use in the Pharmaceutical Industry; Fluorination Approaches; The Development of Csp3-Csp2 Coupling Methodology; Catalytic Amide Bond Forming Methods; Accessing Novel Molecular Motifs and Monomers


PRODUCT DETAILS

ISBN-13: 9781782627869
Publisher: Royal Society of Chemistry
Publication date: July, 2016
Pages: 350
Dimensions: 156.00 x 234.00 x 36.00
Weight: 975g
Availability: Contact supplier
Subcategories: Biochemistry

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