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MORE ABOUT THIS BOOK
Main description:
Activation, inhibition, or destruction of the nervous system or its component parts as a vital tool for the investigation of function has undergone remarkable development; indeed, new approaches have been developed that allow for these actions to be used as therapeutic tools. In Stimulation and Inhibition of Neurons, experts in the field provide an overview of modern methods for generating lesions as well as for stimulating and inhibiting neural pathways. Many new techniques such as optogenetics and the use of the in situ perfused preparation are examined, while, in other sections, the use and validity of more well-known approaches are reassessed. Written for the Neuromethods series, chapters examine their respective topics thoroughly and include the kind of detail and implementation advice that ensures successful results in the laboratory.
Authoritative and cutting-edge, Stimulation and Inhibition of Neurons serves as an ideal guide for researchers seeking to gain further knowledge of the complex functions of the brain.
Contents:
Part I: Novel Experimental Techniques
1. Optogenetic Stimulation of Neurons in the Brainstem of Freely Behaving Rats and Mice
Stephen Abbott
2. Stimulating Peripheral Afferents to Evoke Cardiorespiratory Reflex responses in the In Situ Arterially-Perfused Preparation
Angelina Y. Fong
3. Excitatory Responses to Microinjection of Glutamate Depend on Dose not Volume: A Meta-Analysis of Studies in Rat RVLM
Andrea H. Gaede and Paul M. Pilowsky
4. Acute Activation and Inhibition of the Sympathetic Baroreceptor Reflex
Melissa M.J. Farnham
Part II: Intracellular Signalling
5. Pharmacological Dissection of G Protein-Mediated Second Messenger Cascades in Neurons
Mark C. Bellingham
6. In Vivo Manipulation of Intracellular Signalling Pathways
V.J. Tallapragada
Part III: The Single Neurons
7. Identification of Spinally Projecting Neurons in the Rostral Ventrolateral Medulla In Vivo
Simon McMullan
8. Microionotophoretic Study of Individual Neurons During Intracellular Recording
Qi-Jian Sun and Paul M. Pilowsky
9. Neurobiotin Electroporation for Combined Structural and Functional Analysis of Neurons in Developing Mouse Brain Slices
Refik Kanjhan and Mark C. Bellingham
10. Juxtacellular Neuronal Labelling, Physiological Characterization, and Phenotypic Identification of Single Neurons In Vivo
Anthony J.M. Verberne and Ida J. Llewellyn-Smith
Part IV: Methods for Analysis
11. Analysis of Sympathetic Nerve Activity Analysis of Sympathetic Nerve Activity
Rohit Ramchandra
12. Insight into Autonomic Nervous System Control of Heart Rate in the Rat Using Analysis of Heart Rate Variability and Baroreflex Sensitivity
Cara M. Hildreth, Ann K. Goodchild, and Jacqueline K. Phillips
13. Neurophysiological Recording of the Compound Muscle Action Potential for Motor Unit Number Estimation in Mice
Shyuan T. Ngo and Mark C. Bellingham
Part V: Clinical Focus and Application
14. Animal Models of Neuropathic Pain Due to Nerve Injury
Paul J. Austin and Gila Moalem-Taylor
15. Detection of Sensitized Nerve Responses: Dorsal Root Reflexes, Live Cell Calcium, and ROS Imaging
Karin N. Westlund and Liping Zhang
16. Visual Evoked Potential Recording in Rodents
Yuyi You, Alexander Klistorner, and Stuart L. Graham
17. The Visual Evoked Potential in Humans
Stuart L. Graham and Alexander Klistorner
18. Improving Motor Activation Patterns after Stroke with Wii-Based Movement Therapy
Angelica G. Thompson-Butel, Sarah E. Scheuer, and Penelope A. McNulty
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: November, 2012
Pages: 396
Weight: 7684g
Availability: Available
Subcategories: Neurology, Neuroscience, Physiology
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