Sickle Cell Pain is a panoramic, in-depth exploration of every scientific, human, and social dimension of this cruel disease. This comprehensive, definitive work is unique in that it is the only book devoted to sickle cell pain, as opposed to general aspects of the disease.

The 752-page book links sickle cell pain to basic, clinical, and translational research, addressing various aspects of sickle pain from molecular biology to the psychosocial aspects of the disease.

Supplemented with patient narratives, case studies, and visual art, Sickle Cell Pain’s scientific rigor extends through its discussion of analgesic pharmacology, including abuse-deterrent formulations. The book also addresses in great detail inequities in access to care, stereotyping and stigmatization of patients, the implications of rapidly evolving models of care, and recent legislation and litigation and their consequences.

Part I.    Basic Considerations
1.    Sickle Cell Pain in Historical Perspective
2.    The Hematology of Sickle Cell Pain: A Prototype of Bedside and Bench Interactions
Part II. Sickle Cell Pain Syndromes
3.    Classification of Sickle Cell Pain
4.    The Acute Painful Episode
5.    Acute Regional Pain Syndromes
6.    Chronic Pain Syndromes
7.    Other Pain Syndromes
8.    Munchausen Sickle Cell Painful Episodes
9.    Pharmacology of Analgesics and Adjuvants
10.    Pharmacologic Management of the Patient With Sickle Cell Pain
11.    Pharmacogenetics, Genetics, Epigenetics, and Genetic Markers of Sickle Cell Pain
Part IV. Other Therapeutic Modalities
12.    NonpharmacologicTherapy for Sickle Cell Pain
13.    Diet, Fluids, and Sickle Cell Pain
14.    Preventive and Curative Therapies
Part V. Miscellaneous Aspects of Sickle Cell Pain
15.    Obstetrics, Gynecology, and Sickle Cell Pain
16.    The Adult “Difficult” Patient With Sickle Cell Disease and the Ethics of Sickle Cell Pain
17.    Issues Pertinent to Sickle Cell Pain
18.    Civil Litigation and Sickle Cell Pain
Epilogue
Appendices
Appendix A: Sickle Cell Knowledge Self-Assessment for Medical Personnel
Appendix B: Answers to Appendix A
Appendix C: Names of Drugs in Different Countries
Appendix D: Names of Street Drugs
Appendix E: Sample Consent Form for Chronic Opioid Therapy
Appendix F: Sample Treatment Plan
Appendix G: Breaking News
List of Abbreviations and Acronyms
Glossary