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Regulatory Toxicology
Essentially Practical Aspects
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Main description:

This book covers all aspects of regulatory toxicology - test methods and procedures required for generating data for submission to regulatory authorities. The introductory chapter gives a brief overview of various toxicity studies conducted as per Good Laboratory practices. Important considerations in toxicology testing have been outlined followed by a brief account of fundamental aspects of toxicity testing, animal husbandry, animal welfare and animal alternatives. The book also covers a wide range of experimental procedures including clinical and morphological studies, skin sensitization, teratogenicity, neurotoxicity and carcinogenicity studies, clinical and target organ pathology, inhalation toxicity, mutagenicity and statistical methods. Lastly, there is a chapter on how to manage a GP facility making this book useful for scientific and technical personnel involved in generating data required for registration of products.


Contents:

Introduction / Important Considerations in Toxicology / Principles of Biological Testing in Toxicology / Animal Husbandry and Animal Welfare / Animal Alternatives / Practical Considerations in Toxicology Testing / Target Organ Pathology / Carcinogenicity Studies: Certain Aspects / Genotoxicity Studies: A Concise Account / Neurotoxicity Studies / Reproduction Studies / Statistical Methods in Regulatory Toxicology / Good Laboratory Practices: Managing a GLP Test Facility: Challenges and Clues / Bibliography / Appendices.


PRODUCT DETAILS

ISBN-13: 9788184874174
Publisher: Narosa Publishing House
Publication date: June, 2016
Pages: 260
Weight: 652g
Availability: Available
Subcategories: Pharmacology

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