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Red Blood Cell Alloimmunization After Blood Transfusion
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Main description:

Current pre-transfusion policy requires the patient's serum to be tested for the presence of irregular red blood cell antibodies. In case of an alloantibody, red blood cells lacking the corresponding antigen are transfused after an antoglobulin crossmatch. The aim of the study in this thesis is primarily to investigate whether this policy should change to improve transfusion safety.


Contents:

Contents - 8 1. General Introduction - 10 2. Review of the Literature on red Cell Alloimmunization - 18 3. Alloimmunization to red Blood Cell Antigens after Universal Leucodepletion. A regional multicentre retrospective study - 44 4. The importance of antibodies against loq-incidence RBC Antigens in complete and abbreviated cross-matching - 56 5. Alloimmunization after blood transfusion in patients with hametologic and oncologic diseases - 70 6. Additional RBC alloantibodies after blood transfusion in a nonhematological alloimmunizaed patient cohort: is it time to take precautionary measures? - 88 7. High additional maternal red cell alloimmuzation after RH- and K-Matched intrautertine intravascular transfusions for homolytic disease of the fetus - 102 8. RBC antibody persistence - 116 9. Red vlood cell alloantibodies after transfusion: Factors influencing incidence and specificity - 128 10. general discussion - 144 SUMMARY - 154 SAMENVATTING - 164 CURRICULUM VITAE - 174 PUBLICATIONS - 175


PRODUCT DETAILS

ISBN-13: 9789087280314
Publisher: Leiden University Press
Publication date: December, 2007
Pages: 176
Dimensions: 156.00 x 234.00 x 10.00
Weight: 283g
Availability: Not available (reason unspecified)
Subcategories: General Issues

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