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Magnetic Resonance Imaging
Methods and Biologic Applications
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Main description:

Leading experts in the use of MRI explain its basic principles and demonstrate its power to understand biological processes with numerous cutting-edge applications. To illustrate its capability to reveal exquisite anatomical detail, the authors discuss MRI applications to developmental biology, mouse phenotyping, and fiber architecture. MRI can also provide information about organ and tissue function based on endogenous cantrast mechanisms. Examples of brain, kidney, and cardiac function are included, as well as applications to neuro and tumor pathophysiology. In addition, the volume demonstrates the use of exogenous contrast material in functional assessment of the lung, noninvasive evaluation of tissue pH, the imaging of metabolic activity or gene expression that occur on a molecular level, and cellular labeling using superparamagnetic iron oxide contrast agents.


Contents:

I. Introduction

Introduction to Magnetic Resonance Imaging and Spectroscopy

Pippa Storey

Magnetic Resonance Microscopy: Concepts, Challenges, and State-of-the-Art

Barjor Gimi

II. Anatomy

Magnetic Resonance Imaging of Embryonic and Fetal Development in Model Systems

Eric T. Ahrens, Mangala Srinivas, Saverio Capuano, Hyagriv N. Simhan, and Gerald P. Schatten

Mouse Morphological Phenotyping With Magnetic Resonance Imaging

X. Josette Chen

Magnetic Resonance Microscopy of Mouse Brain Development

Susumu Mori, Jiangyang Zhang, and Jeff W. M. Bulte

III. Physiology

Quantitative Perfusion Imaging Using Arterial Spin Labeling

Donald S. Williams

Physiology of Functional Magnetic Resonance Imaging: Energetics and Function

Ikuhiro Kida and Fahmeed Hyder

Functional Magnetic Resonance Imaging of the Kidney

Pottumarthi V. Prasad

Cardiac Magnetic Resonance Spectroscopy: A Window for Studying Physiology

Michael Horn

IV. Pathophysiology

Application of Magnetic Resonance Imaging to Study Pathophysiology in Brain Disease Models

Rick M. Dijkhuizen

Magnetic Resonance Imaging of Tumor Physiology

Arvind P. Pathak

Magnetic Resonance Imaging in Preclinical Drug Development

Matthew D. Silva and Sudeep Chandra

V. Novel Contrast Agents and Mechanisms

Hyperpolarized Gas and Oxygen-Enhanced Magnetic Resonance Imaging

Vu M. Mai

Tissue pH Measurement by Magnetic Resonance Spectroscopy and Imaging

Natarajan Raghunand

Biological Applications of Manganese-Enhanced Magnetic Resonance Imaging

Robia G. Pautler

Targeted Magnetic Resonance Imaging Contrast Agents

Shelton D. Caruthers, Patrick M. Winter, Samuel A. Wickline, and Gregory M. Lanza

Design and Characterization of Magnetic Resonance Imaging Gene Reporters

Angelique Louie

Intracellular Endosomal Magnetic Labeling of Cells

Jeff W. M. Bulte

Index


PRODUCT DETAILS

ISBN-13: 9781627038126
Publisher: Springer (Humana Press Inc.)
Publication date: November, 2014
Pages: 464
Weight: 706g
Availability: Available
Subcategories: Anatomy, Biochemistry, Neurology, Radiology
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