Contents:

PART I: INTRODUCTION 1. Overview of the Immune System 2. Cells, Organs, and Microenvironments of the Immune System 3. Receptors and Signaling: B and T Receptors 4. Receptors and Signaling: Cytokine and Chemokine PART II: INNATE IMMUNITY 5. Innate Immunity 6. The Complement System PART III: ADAPTIVE IMMUNITY: ANTIGEN RECEPTORS AND MHC 7. Organization and Expression of Lymphocyte Receptor Genes 8. The Major Histocompatibility Complex and Antigen Presentation PART IV: ADAPTIVE IMMUNITY: DEVELOPMENT 9. T-Cell Development 10. B-Cell Development PART V: ADAPTIVE IMMUNITY: EFFECTOR RESPONSES 11. T-cell Activation, Differentiation, and Memory 12. B-cell Activation, Differentiation, and Memory 13. Effector Responses: Cell and Antibody-Mediated Immunity 14. Immune Responses in Time and Space PART VI: THE IMMUNE SYSTEM IN HEALTH AND DISEASE 15. Inflammation: Allergy and Hypersensitivities 16. Tolerance, Autoimmunity, and Transplantation 17. Infectious Diseases and Vaccines 18. Immunodeficiency Disorders 19. Cancer and the Immune System PART VII: EXPERIMENTAL METHODS 20. Experimental Methods