Main description:

Full-field optical coherence microscopy (FF-OCM) is an imaging technique that provides cross-sectional views of the subsurface microstructure of semitransparent objects. The technology is based on low-coherence interference microscopy, which uses an area camera for en face imaging of the full-field illuminated object. FF-OCM benefits from the lateral imaging resolution of optical microscopy along with the capacity of optical axial sectioning at micrometer-scale resolution. The technique can be employed in diverse applications, in particular for non-invasive examination of biological tissues.

This handbook is the first to be entirely devoted to FF-OCM. It is organized into four parts with a total of 21 chapters written by recognized experts and major contributors to the field. After a general introduction to FF-OCM, the fundamental characteristics of the technology are analyzed and discussed theoretically. The main technological developments of FF-OCM for improving the image acquisition speed and for endoscopic imaging are presented in part II. Extensions of FF-OCM for image contrast enhancement or functional imaging are reported in part III. The last part of the book provides an overview of possible applications of FF-OCM in medicine, biology, and materials science.

A comprehensive compilation of self-contained chapters written by leading experts, this handbook is a definitive guide to the theoretical analyses, technological developments, and applications of FF-OCM. Using the rich information the book is replete with, a wide range of readers, from scientists and physicists to engineers as well as clinicians and biomedical researchers, can get a handle on the latest major advances in FF-OCM.

Contents:

Introduction to Full-Field Optical Coherence Microscopy. Theory of Imaging and Coherence Effects in Full-Field Optical Coherence Microscopy. Spatiotemporal Coherence Effects in Full-Field Optical Coherence Tomography. Cross Talk in Full-Field Optical Coherence Tomography. Signal Processing Methods in Full-Field Optical Coherence Microscopy. High-Speed Image Acquisition Techniques of Full-Field Optical Coherence Tomography. Toward Single-Shot Imaging in Full-Field Optical Coherence Tomography. Frequency Domain Full-Field Optical Coherence Tomography. Full-Field OCM for Endoscopy. Full-Field Optical Coherence Tomography and Microscopy Using Spatially Incoherent Monochromatic Light. Real-Time and High-Quality Online 4D FF-OCT Using Continuous Fringe Scanning with a High-Speed Camera and FPGA Image Processing. Digital Interference Holography for Tomographic Imaging. Technological Extensions of Full-Field Optical Coherence Microscopy for Multicontrast Imaging. Spectroscopic Full-Field Optical Coherence Tomography. Multiwavelength Full-Field Optical Coherence Tomography. Dual-Modality Full-Field Optical Coherence and Fluorescence Sectioning Microscopy: Toward All Optical Digital Pathology on Freshly Excised Tissue. Full-Field Optical Coherence Tomography for Rapid Histological Evaluation of ex vivo Tissues. FF-OCT Imaging: A Tool for Human Breast and Brain Tissue Characterization. Full-Field Optical Coherence Microscopy in Ophthalmology. Investigation of Spindle Structure and Embryo Development for Preimplantation Genetic Diagnosis by Subcellular Live Imaging with FF-OCT. FF-OCT for Nondestructive Material Characterization and Evaluation.