Geriatric Neurology, Volume 152 serves as an update on the basic biological and behavioral mechanisms underlying the aging process, with an emphasis on neurological aging and state-of-the-art reviews on our understanding of the vascular, cognitive, neurodegenerative and neuropsychiatric diseases in the elderly. The demographic aging of society has increased attention on all of these topics, and research in geriatrics and neurodegenerative diseases has resulted in a massive amount of new basic and clinical knowledge of the aging nervous system, the cellular bases of brain aging, and explication of mechanisms of neurodegenerative diseases. The cognitive changes associated with normal aging, the fundamentals and rationale for cognitive and neuropsychological assessment in the elderly, and the neurological examination and its focus in the older patients are accompanied by some of the broader issues of concern to geriatrics: the epidemiology of aging, the interactions between neurological diseases and medical co-morbidities in the elderly, models of care and prevention of aging-associated diseases. Developed with an eye to providing both the basic underpinnings of age-related changes and the clinical information to aid with diagnostics and treatment, the book serves as a useful volume for students, basic and translational scientists, and practicing clinicians in understanding and treating common neurological disorders in the elderly.
Section I: Foundations and Principles of Geriatric neurology 1. Geriatric Neurology: Progress over the Past 20 years 2. Molecular bases of aging and diseases in the elderly: current understanding 3. Psychopharmacology and Pharmacokinetics 4. Models of Care 5. Neurological Examination in the Elderly 6. Cognitive and Neuropsychological Evaluation the Elderly 7. Medical Comorbidities and Neurological Disorders 8. Syncope and Autonomic Dysfunction 9. Epidemiology of Aging and Associated Neurological Disorders 10. Psychology and Psychodynamics of Aging 11. Cognitive and Brain Reserve in Aging 12. Structure and Function of the Brain - Neuroimaging 13. Neuroimaging in Aging and Neurological Diseases 14. Prevention of Aging-Associated Diseases Section II: Neurological Disorders of Late-Life Neurodegenerative Diseases: 15. Alzheimer's disease 16. Lewy Body Dementia and Parkinson's Disease 17. Frontotemporal Lobar Dementia 18. Other Dementias PSP, Posterior Cortical 19. Down's syndrome 20. CTE 21. Delirium 22. Cerebrovascular Disease and Vascular Dementia 23. Stroke 24. Gait disturbances, vascular, spinal, system disorders 25. Late life depression in the elderly 26. Neuropsychiatric disturbances in the elderly Movement Disorders: 27. HyperkinetIc 28. Bradykinetic (Parkinson's) 29. Epilepsy & Episodic Disorders in Aging 30. Sleep Disorders in the Elderly Section III: General Topics in Geriatric Neurology 31. Urological function and dysfunction in aging: diagnosis and treatment 32. Rehabilitation 33. Palliative Care and End of Life Care 34. Headache 35. Driving in the Elderly in Health and Disease