Main description:

Endothelium, the new volume in the Advances in Pharmacology series, presents readers with a variety of chapters that cover various endothelium-derived mediators and their changes with gender, and during vascular development, senescence, and hypertensive disorders.

Topics include endothelium, nitric oxide, gap junctions, potassium channels, endothelin, vascular development, vascular permeability, gender, aging, and preeclampsia. With contributions from the best authors in the field, the volume is an essential resource for pharmacologists, immunologists, and biochemists alike.

Contents:

1. The Endothelium-Dependent Nitric Oxide-cGMP Pathway Fabiola Zakia Monica, Ka Bian and Ferid Murad 2. Transcriptional and Post Translational Regulation of eNOS in the Endothelium David J.R. Fulton 3. Endothelial Small and Intermediate Conductance K Channels and Endothelium-Dependent Hyperpolarization as Drug Target in Cardiovascular Disease Ralf Koehler, Aida Olivan-Viguera and Heike Wulff 4. Epoxyeicosatrienoic Acids and 20-Hydroxyeisosatetraenoic Acid on Endothelial and Vascular Function John D Imig 5. Endothelin-1 Biosynthesis, Signaling and Vasoreactivity Martin Houde, Louisane Desbiens and Pedro D'Orleans-Juste 6. Endothelium-Dependent Contractions: Prostacyclin and Endothelin-1, Partners in Crime? Oliver Baretella and Paul M. Vanhoutte 7. Communication Through Gap Junctions in the Endothelium Kjestine Schmidt, Rainer Windler and Cor De Wit 8. Molecular Signaling Pathways Controlling Vascular Tube Morphogenesis and Pericyte Induced Tube Maturation in 3D Extracellular Matrices Stephanie L.K. Bowers, Pieter R. Norden and George E. Davis 9. Stress-Induced Premature Senescence of Endothelial and Endothelial Progenitor Cells Michael S. Goligorsky and Karen Hirschi 10. Estrogens and Coronary Artery Disease: New Clinical Perspectives Matthias R. Meyer and Matthias Barton 11. Mechanisms of Endothelial Dysfunction in Hypertensive Pregnancy and Preeclampsia Jose S. Possomato-Vieira and Raouf A. Khalil