Host Response to Biomaterials: The Impact of Host Response on Biomaterial Selection explains the various categories of biomaterials and their significance for clinical applications, focusing on the host response to each biomaterial. It is one of the first books to connect immunology and biomaterials with regard to host response. The text also explores the role of the immune system in host response, and covers the regulatory environment for biomaterials, along with the benefits of synthetic versus natural biomaterials, and the transition from simple to complex biomaterial solutions. Fields covered include, but are not limited to, orthopaedic surgery, dentistry, general surgery, neurosurgery, urology, and regenerative medicine.
Foreword Preface 1. Factors Which Affect the Host Response to Biomaterials 2. Perspectives on the inflammatory healing, and foreign body response to biomaterials and medical devices 3. The Biocompatibility of Implant Materials 4. Host Response to naturally der5. Molecular events at tissue-biomaterial interface 6. Macrophage Plasticity and Polarization: Relevance to Biomaterials 7. Role of dendritic cells in response to biomaterials 8. The acquired immune system response to biomaterials, including both naturally occurring and synthetic biomaterials 9. Fibrotic response to biomaterials and all associated sequence of fibrosis 10. Human Anti-Gal and Anti-Non-Gal Immune Response to Porcine Tissue Implants 11. Aging and the Host Response to Implanted Biomaterials 12. Host Response to Orthopedic Implants (Metals and Plastics) 13. Host Response to surgical mesh materials used for pelvic floor reconstruction 14. Methods Used to Evaluate the Host Responses to Medical Implants In Vivo