In this book, the authors discuss the biophysical characteristics of Dendritic cells (DCs) at various differentiation stages and in tumor microenvironments in detail. A type of Chinese traditional herb, which can improve the biophysical and microrheological properties of DCs, is also introduced. DCs are potent and specialized antigen-presenting cells that play a crucial role in initiating and amplifying both the innate and adaptive immune responses. The biophysical and microrheological characteristics of DCs are important for their motility and normal immune function. In tumor microenvironments, the motility and immune functions of DCs are impaired, but the mechanisms are largely unknown. This book offers researchers a comprehensive and deep insight into the biophysical characteristics of DCs and may also help to improve the efficiency of anti-tumor therapy based on DCs.
Summarizing the cutting-edge studies on biophysical properties of DCs
Comprehensively overviewing the biophysical properties of DCs at different differentiation stage and tumor microenvironment
Exploring the immune escape mechanisms of tumor cells Provide a potential clinical treatment for tumors based on DCs
Summary.- Introduction.- The measurement protocols of cell biophysical characteristics.- Biophysical characteristics of dendritic cells at different differentiation stages.- Biophysical characteristics of dendritic cells in tumor microenvironment.- Effects of Chinese traditional herbs on dendritic cells.- Future perspectives