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The Mouse Nervous System provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and organization of the area they have chosen to study. The Mouse Nervous System offers a wealth of new information for experienced anatomists who work on mice. The book serves as a valuable resource for researchers and graduate students in neuroscience.Systematic consideration of the anatomy and connections of all regions of the brain and spinal cord by the authors of the most cited rodent brain atlasesA major section (12 chapters) on functional systems related to motor control, sensation, and behavioral and emotional statesA detailed analysis of gene expression during development of the forebrain by Luis Puelles, the leading researcher in this areaFull coverage of the role of gene expression during development and the new field of genetic neuroanatomy using site-specific recombinasesExamples of the use of mouse models in the study of neurological illness
This second of two volumes on Cancer Imaging covers the three major topics of imaging instrumentation, general imaging applications, and imaging of a number of human cancer types. Where the first volume emphasized lung and breast carcinomas, Volume 2 focuses on prostate, colorectal, ovarian, gastrointestinal, and bone cancers. Although cancer therapy is not the main subject of this series, the crucial role of imaging in selecting the type of therapy and its post-treatment assessment are discussed. The major emphasis in this volume is on cancer imaging; however, differentiation between benign tumors and malignant tumors is also discussed. This volume is sold individually, and Cancer Imaging, Volume 1 [ISBN: 978-0-12-370468-9] sells separately for $189 and also as part of a two volume set [ISBN: 978-0-12-374212-4] for $299.* Concentrates on the application of imaging technology to the diagnosis and prognosis of prostate, colorectal, ovarian, gastrointestinal, and bone cancers* Addresses relationship between radiation dose and image quality * Discusses the role of molecular imaging in identifying changes for the emergence and progression of cancer at the cellular and/or molecular levels
This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology.NEW TO THE THIRD EDITION:* Covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies* General comments to each chapter about the relevance of pathological findings to humans* Provides essential information that can help decide the relevance of particular lesions for patients
Focuses on the field of regeneration in the Central Nervous System (CNS) from molecular, systems, and disease-based perspective. This book covers numerous areas in detail, and gives special emphasis to discussions of movement disorders such as Parkinson's disease, Alzheimer's disease, and spinal cord injury.
Offers information on explosion and blast injury patterns, as well as the mechanism of blast-induced injuries. This book covers topics such as the epidemiology of blast and explosion injury, pathology and pathophysiology, and the modeling and mechanism of injury.