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C-H Bond Activation in Organic Synthesis
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Main description:

Greener than conventional methods, C-H activation methods have flourished during the last decade and become especially attractive to organic chemists. Edited by a practioner in this rapidly developing field, C-H Bond Activation in Organic Synthesis provides an overview of this exciting playground of chemistry. The book summarizes the state of the art in C-H activation for functionalization, enabling you to carry out reactions in the most environmentally friendly fashion with the least contamination of by-products. The most popular C-H activation reactions are catalyzed by transition metals. This book dedicates a chapter to each of the following catalysts: palladium, rhodium, nickel, iron, copper, and cobalt. In addition, it covers radical-mediated C-H activation, fluorination via C-H activation, and C-H activation of heterocycles. Using a pedagogically practical approach, each chapter is divided by the transition metal catalyst, not a specific transformation. This gives you an up-to-date review of the most important topics of C-H activation.
The area of C-H activation has experienced a flurry of activity over the past two decades, so the time is right for a resource that summarizes these powerful tools with which you can design and construct heteroaromatic molecules. Thus, direct C-H functionalization methods are expected to continue to greatly contribute to the mission of green chemistry: low-energy, waste-free, and atom-economic transformations for the synthesis of organic materials and biologically active molecules in the twenty-first century. Using this book, you can carry out environmentally friendly reactions that enable the conversion of cheap and abundant alkanes into valuable functionalized organic compounds.


Contents:

Introduction Marion H. Emmert Radical-Mediated C-H Bond Activation Adam M. Azman Pd-Catalyzed C-H Functionalization Jesse D. Carrick Rhodium-Catalyzed C-H Activation Micheal Fultz Nickel-Catalyzed C-H Activation Andrew C. Williams Iron-Catalyzed C-H Activation Narendra B. Ambhaikar Copper-Mediated C-H Activation Nadia M. Ahmad Cobalt-Catalyzed C-H Activation Eric J. Medici and Nicole L. Snyder Fluorination and Trifluoromethylation of Arenes and Heteroarenes via C-H Activation Ji Zhang and Timothy T. Curran C-H Activation of Heteroaromatics Donna A. A. Wilton


PRODUCT DETAILS

ISBN-13: 9781482233117
Publisher: Elsevier (Apple Academic Press Inc.)
Publication date: March, 2015
Pages: 352

Subcategories: Biochemistry