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Biodrug Delivery Systems
Fundamentals, Applications and Clinical Development
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Main description:

Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development presents the work of an international group of leading experts in drug development and biopharmaceutical science who discuss the latest advances in biodrug delivery systems and associated techniques. The book discusses components of successful formulation, delivery, and production of biodrugs, which include sophisticated plants and complex processes, a well-trained and knowledgeable staff, and proper quality control. In addition, the authors examine: * ADME (Absorption, Metabolism, Distribution, and Elimination of biodrugs) * Directing and influencing the successful development of currently marketed best-selling biodrugs * Routes of administration * Mechanisms of biodrug absorption * Alternative possibilities for drug delivery routes * Formulationson the market from the perspective of industry personnel involved in biodrug development


Overview of Biodrug Delivery System Issues in Biodrug Delivery System Pharmacokinetic Consideration of Biodrugs Specific Route of Delivery Parenteral Delivery Brain Delivery Ocular Delivery Nasal Delivery Buccal Delivery Pulmonary Delivery Transdermal Delivery Colon Delivery Oral Delivery Cellular Delivery Delivery Systems Targeting: PK Consideration Monoclonal Antibody Receptor-Mediated Endocytosis Bioadhesive Delivery System Modified Release Delivery System Nanoparticulate Delivery System Lipid-Based Delivery System Implantable Delivery System Modifying the Physiochemical Nature of Biodrugs Regulatory Perspective of Biodrug Development Development of Biodrug Products Leuplin ANP (Atrial Natriuretic Peptide) Amylin And GLP-1 Agonists GHRP-2 (Growth Hormone Releasing Peptide) Endothelin Receptor Antagonist Angiotensin II Receptor Antagonist Insulin (Inhalation) Calcitonin Sandstatin LAR Interferon Vaccine Perspective of Biodrug Products


ISBN-13: 9781420086713
Publisher: Informa Healthcare
Publication date: December, 2009
Pages: 488

Subcategories: Pharmacology