This atlas elucidates the role of the neuronal component in normal cardiovascular function and cardiac disorders and discusses the currently available imaging targets and probes. It provides a foundation in cardiac neuronal imaging and image processing and serves as a guide in the effective utilization of these techniques in clinical and research settings. The atlas discusses the principles of autonomic control in the regulation of cardiac function and disease; chemistry and biology of radiotracers designed to target changes in the myocardial sympathetic and parasympathetic innervation as a function of disease or treatment; neuronal imaging in heart failure and reverse remodeling and the use of PET imaging in quantification of cardiac innervation; cardiac sympathetic innervation in ventricular arrhythmias and device therapy; conditions that affect the autonomic nervous system; and the role of myocardial blood flow and cardiac neuronal imaging in denervation and reinnervation in cardiac transplant recipients.
Featuring full-color illustrations, schematic diagrams, and diagnostic algorithms, Atlas of Cardiac Innervation is a valuable resource for cardiologists, radiologists, nuclear medicine physicians, and electrophysiologists.
Autonomic Innervation System in the Heart: Anatomy and Molecular Biology.- Neural Control of Cardiac Function in Health and Disease.- Chemistry and Biology of Radiotracers Designed to Target Changes in the Myocardial Sympathetic and Parasympathetic Nervous Systems as a Function of Disease or Treatment.- Neuronal Imaging in Heart Failure.- PET Imaging and Quantitation of Cardiac Innervation.- Neuronal Imaging and Reverse Remodeling.- Neuronal Imaging, Ventricular Arrhythmias, and Device Therapy in Heart Failure.- Cardiac Sympathetic Innervation and Ablation of Ventricular Tachycardia.- Dysautonomia: From the Brain Disorders to Neuropathies (including Diabetes).- Cardiac Transplantation: Denervation, Reinnervation, and Myocardial Blood Flow.