Main description:

A biography of tuberculosis, an ancient disease - but still a present danger.

Tuberculosis has twisted through the millennia hand-in-hand with humanity, leaving its marks on our culture, our history and our DNA, from the birth of Homo sapiens right up to the present day. TB continues to kill more people than any other infectious agent; it may be an ancient disease, but TB is not a disease of history.

In Catching Breath, Kathryn Lougheed asks what has made Mycobacterium tuberculosis such a successful bacterium, and how we can use this knowledge to consign it to the history books. We follow its path through the ages, from its time gathering strength as a latent infection of hunter-gatherers to its rise alongside human urbanisation and industrialisation, and learn just how connected human history is to TB - from an Ancient Egyptian murder mystery and the rumours of the first vampires to a tragedy set in the Amazon rainforest.

Catching Breath looks at the hidden biology behind the interactions of Mycobacterium tuberculosis with its human host, and shows how drug resistance, the HIV epidemic, poverty and inequality work together to ensure that TB remains one of the most serious problems in world medicine.

If we can understand the makings of TB, then maybe we can find a way to unmake it.

Contents:

1. Bringing the Dead Back to Life - Diagnosing TB in ancient remains

2. Growing Up Together- How Mycobacterium tuberculosis and Homo sapiens co-evolved

3. Populating the Planet- How TB spread around the world, and continues to do so today

4. Altered Evolution - How the human immune system has been shaped through natural selection by TB

5. Leaving Scars - TB doesn't induce natural immunity, so vaccination doesn't work
6. The Patient Pathogen - Mycobacterium tuberculosis can enter into a state of hibernation in the human lung

7. The Drugs Don't Work - How do you kill something that is barely alive?

8. Killing the Unkillable - New drugs for bad bugs

9. Third-world London - How TB is creeping in through the cracks

10. Pale and Beautiful - Changing attitudes towards TB

10. My Cat Infected Me with TB - TB in the news

11. The People Behind the Disease - Personal stories of TB survival and recovery

12. A Losing Battle? - How are we going to win the war against TB?