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Alternatives to Blood Transfusion in Transfusion Medicine
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Main description:

Meeting the needs of patients while minimizing blood transfusions requires special expertise, precise monitoring and innovative techniques. This cutting–edge resource covers all the important clinical aspects of transfusion medicine in diverse clinical settings, with a special emphasis on alternatives to transfusion.

Edited by a multidisciplinary team consisting of a transfusion specialist, an anesthesiologist and an intensive care specialist this book is endorsed by the Network for Advancement of Transfusion Alternatives. The contributors review the appropriate use of fluids and of blood products, and describe the latest treatment options available to decrease the need for allogeneic blood products including:



  • Argon beam

  • Cell saver

  • Harmonic scalpel

  • Normovolemic haemodilution

  • Synthetic erythropoietin

  • Antifibrinolytics

  • Recombinant factor VIIa

  • Advanced monitoring of hemostasis

  • Intravenous iron


The new edition is a key reference source for all those involved in the practice of blood management and conservation.


Back cover:

Meeting the needs of patients while minimizing blood transfusions requires special expertise, precise monitoring and innovative techniques. This cutting–edge resource covers all the important clinical aspects of transfusion medicine in diverse clinical settings, with a special emphasis on alternatives to transfusion.

Edited by a multidisciplinary team consisting of a transfusion specialist, an anesthesiologist and an intensive care specialist this book is endorsed by the Network for Advancement of Transfusion Alternatives. The contributors review the appropriate use of fluids and of blood products, and describe the latest treatment options available to decrease the need for allogeneic blood products including:



  • Argon beam

  • Cell saver

  • Harmonic scalpel

  • Normovolemic haemodilution

  • Synthetic erythropoietin

  • Antifibrinolytics

  • Recombinant factor VIIa

  • Advanced monitoring of hemostasis

  • Intravenous iron


The new edition is a key reference source for all those involved in the practice of blood management and conservation.


Contents:

Contributors List ix


Part 1 History and Development of Transfusion Medicine 1


1 From Blood Transfusion to Transfusion Medicine 3
Alice Maniatis


Part 2 Allogeneic Blood Usage Risks and Benefits 9


2 Allogeneic Blood Components 11
Rebecca Cardigan & Sheila MacLennan


3 Current Information on the Infectious Risks of Allogeneic Blood Transfusion 21
Alan D. Kitchen & John A. J. Barbara


4 Immunological Complications of Blood Transfusion 31
Clare Taylor Cristina Navarrete & Marcela Contreras


5 Immunomodulation and Allogeneic Blood Transfusion 47
Marloes Waanders Leo Van De Watering & Anneke Brand


6 Pathogen Inactivation of Blood Components 60
Chris Prowse


7 The Benefits of Allogeneic Erythrocyte Transfusion: What Evidence Do We Have? 68
Neil Soni & Benjamin Thomas


Part 3 Volume Replacement 83


Section 1 Plasma and Albumin 85


8 Plasma and Albumin 87
Philippe L. Baele


Section 2 Crystalloids and Synthetic Colloids 109


9 Pharmacology of Intravenous Fluids 111
Michael F.M. James


10 Crystalloids versus Colloids: The Controversy 119
Hengo Haljamäe


11 Effects of Synthetic Colloids on Hemostasis 137
Sibylle A. Kozek–Langenecker & Gisela Scharbert


12 Hydroxyethyl Starch and Renal Dysfunction 150
Laurent Jacob Nicholas Heming & Bertrand Guidet


13 Choice of a Synthetic Colloid for Surgery 158
Joachim Boldt


14 Choice of Colloid for Intensive Care Patients 168
Yasser Sakr & Yalcin Inel


15 Hypertonic Saline Solutions for the Initial Treatment of Patients with Traumatic Injuries 179
Charles E. Wade & Michael A. Dubick


16 Hyperchloremic Acidosis 194
Edward Burdett & Andre Vercueil


Part 4 Tolerance of Anemia 203


17 Basic Principles of Oxygen Transport and Calculations 205
Jean–Louis Vincent Pongdhep Theerawit & Davide Simion


18 Assessment of Tissue Oxygenation 210
Michael Piagnerelli Ann Dierick & Philippe Van der Linden


19 Tissue Oxygenation and Blood Transfusion 218
Stefan Suttner & Joachim Boldt


20 Anemia and Cardiovascular Disease 229
Antonis S. Manolis Spyridon Koulouris Kostas Triantafyllou Dimitris Sakellariou Sokratis Pastromas & Helen Melita


Part 5 Perioperative Hemostasis 253


21 Monitoring of Hemostasis in the Perioperative Setting 255
Sibylle A. Kozek–Langenecker & Eva Schaden


22 Antifibrinolytics in Open–Heart Surgery 267
Wulf Dietrich


23 Efficacy and Safety of Recombinant Activated Factor VII to Control Bleeding in Nonhemophiliac Patients 278
Jean–François Hardy Sylvain Bélisle & Philippe Van der Linden


Part 6 Transfusion Triggers 293


24 Role of Hemoglobin/Hematocrit 295
Kristine J. Guleserian Hae W. Kim Bruce Pearce Arkadiy Pitman & A. Gerson Greenburg


25 Calculation of Blood Loss 303
Mark E. Brecher


26 Management of Massive Transfusion 313
Jean–François Hardy & Marc Samama


Part 7 Alternatives to Allogeneic Blood Transfusion 329 Section 1 Pharmaceutical Approaches 331


27 Iron Deficiency: Causes Diagnosis and Management 335
Manuel Muñoz José Antonio García–Erce & Elvira Bisbe


28 Current Status of Perisurgical Erythropoietin Therapy 350
Lawrence T. Goodnough


29 Erythropoietin and Iron Therapy in Patients with Renal Failure 357
Lucia Del Vecchio & Francesco Locatelli


30 Hemoglobin–based Blood Substitutes 368
G. Deby–Dupont Bernadette Remy & Maurice Lamy


31 Perfluorocarbon Emulsions 380
Pedro Cabrales


Section 2 Surgical Techniques 389


32 Minimally Invasive Cardiac Surgery: Impact on Blood Loss and Transfusion 391
He Tao & Fraser Rubens


33 Adjunctive Strategies to Impact Blood Transfusion in Cardiac Surgery 408
L. Ressler & Fraser Rubens


Section 3 Anesthetic Techniques 419


34 Anesthetic Techniques to Reduce Blood Loss 421
Dafydd Thomas


35 Controlled Hypotension Decreases Blood Transfusion Requirement: Fact or Fallacy? 430
Richard P. Dutton


36 Acute Normovolemic Hemodilution 439
Javad Bidgoli & Philippe Van der Linden


37 Hyperoxic Hemodilution 450
Jens Meier Konrad Messmer & Oliver Habler


38 Intraoperative and Postoperative Cell Salvage 458
Ernil Hansen & Hans Gombotz


Section 4 Special Settings 475


39 Anemia and Red Blood Transfusion in Critical Care 477
Tim Walsh


40 Red Blood Cell Transfusions and Alternatives to Treat the Anemia of Prematurity 490
Ronald G. Strauss


41 Transfusion Alternatives in Orthopedic Surgery 498
Manuel Muñoz José Antonio García–Erce & Jorge Cuenca


42 Transfusion Alternatives in Obstetrics 509
Christian Breymann


Part 8 Legal and Ethical Issues in Transfusion Medicine 521


43 Ethical Aspects of Informed Consent: American Models 523
Ronald E. Domen


44 Blood Transfusions Jehovah s Witnesses and the American Patients Rights Movement 531
Charles H. Baron


Part 9 Cost Issues 557


45 The Cost and Cost–Effectiveness of Allogeneic and Autologous Blood 559
Brian Custer


46 Autologous Blood Predonation in Cardiac Surgery 569
Wulf Dietrich


47 Cost–Effectiveness of Pharmacological Alternatives 575
Dean Fergusson & Brian Hutton


Index 581


PRODUCT DETAILS

ISBN-13: 9781405163217
Publisher: John Wiley & Sons Ltd (Wiley–Blackwell)
Publication date: October, 2010
Pages: 608
Dimensions: 197.00 x 253.00 x 39.77
Weight: 1386g
Availability: Available
Subcategories: Diseases and Disorders, Haematology

MEET THE AUTHOR

Professor Alice Maniatis, Haematology Department of Internal Medicine, University of Greece, Athens, Greece and former President of Network for Advancement of Transfusion Alternatives (NATA).

Dr Jean–Francois Hardy, Department of Anesthesia, Montreal Heart Institute, Quebec, Canada and on the Board of Directors of NATA.


Dr Phillipe van der Linden, Department of Anesthesiology and Intensive Care, Brussels, Belguim and on the Board of Directors of NATA.

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