Main description:

Interest in the chemistry, biological properties and healthful benefits of conjugated linoleic acid (CLA) continues to grow. The number of peer reviewed publications produced on CLA since the 2003 publication of Advances in Conjugated Linoleic Acid Research, Volume 2, has more than doubled. It is likely that CLA will be used in the future in many more studies related to diseases such as cancer, atherosclerosis, and diabetes. This text provides comprehensive coverage of this area of research. Sections include material on biosynthesis and metabolic processes, techniques of determination of individual isomers, diversity of CLA, and effects of CLA isomers in humans.

Contents:

BIOSYNTHESIS AND METABOLIC PROCESSES
Conjugated Linoleic Acid Synthesis within the Gut Microbial Ecosystem of Ruminants
Detection of Partial b-Oxidation Products of Conjugated Linoleic Acid Isomers and Their Metabolites in Animals and Humans

TECHNIQUES OF DETERMINATION OF INDIVIDUAL ISOMERS
Syntheses of Conjugated Linoleic Acids
Systematic Analysis of trans and Conjugated Linoleic Acids in the Milk and Meat of Ruminants
New Developments in Silver Ion and Reverse Phase HPLC of Conjugated Linoleic Acid
Structural Characterization of Conjugated Linoleic Acid Methyl Esters with Acetonitrile Chemical Ionization Tandem Mass Spectrometry

DIVERSITY OF CLA
Growth Inhibition and Apoptotic Cell Death of Cancer Cells Induced by Conjugated Linoleic Acid
Modulatory Properties of Conjugated Linoleic Acid on Inflammation and Immune Function: Cellular and Molecular Mechanisms
Conjugated Linoleic Acid in Hypertension
Antioxidative Activity of Conjugated Linoleic Acid Determined by ESR

EFFECTS OF CLA ISOMERS IN HUMANS
An Overview of the Effects of Conjugated Linoleic Acid on Body Weight and Body Composition in Humans
Conjugated Linoleic Acid in Healthy and Cancerous Human Tissues
Lipid-Lowering Actions of trans-10, cis-12 Conjugated Linoleic Acid in Primary Cultures of Human (Pre)Adipocytes
Safety Data on Conjugated Linoleic Acid from Animal Studies: An Overview