Main description:

Mitochondria are among the most important of eukaryotic cell organelles, often referred to as the "powerhouse" of the cell, because of the role they play in providing energy for cellular function. This book synthesizes what is known mitochondrial dynamics, including the fusion and fission of mitochondria, mitophagy (the destruction of damaged mitochondria), and the role of mitochondrial dynamics in disease such as Parkinson's disease and diabetes--among other topics. The volume is designed to appeal to molecular biologists, cell physiologists and anyone interested in the role mitochondria play in cell physiological function.

Contents:

History Of Mitochondrial Dynamic Research. Molecular Regulation Of Mitochondrial Fission And Fusion . Mitochondrial Dynamics In Neuronal Cells. Mitochondrial Fission And Mitochondrial Import. Mitophagy In Yeast. Mitophagy As A Mechanism Against Oxidative Stress, Mitochondrial Dysfunction, And Aging. Molecular Signaling Towards Mitophagy. Mitophagy And Parkinson's Diseases. Mirna Regulation Of Mitochondrial Dynamics. Mitochondrial Fusion And Fission In The Control Of Apoptosis. Structural Insights Towards Mitochondrial Dynamics. Mitochondrial Shape, Functions And The Cytoskeleton. Mitochondria and ER Conjunction. Mitochondrial Dynamics And Diabetes. Mitochondrial Dynamics And Parkinson's Diseases. Mitochondrial Dynamics And Cancer. Pink1 In Dynamics. Mitochondrial Morphology And Dynamics. Mitochondrial Dynamics and mtDNA Inheritance. The Interplay Between Mitochondrial Dynamics and Mitophagy. Mitochondrial Ca2+ And Dynamics In Cardiac Muscle Cells. Mitochondria Dynamics And Oxidative Signaling by cAMP, AKAPs And The Proteasome. Structure And Dynamics Of The Mitochondrial Inner Membrane Cristae. Mitochondria And Peroxisome Connection. Mitochondrial Dynamics In Cell Death And Neurodegeneration. Mitochondrial Dynamics and mtDNA Inheritance.