Main description:

As there are a number of nuances in terms of how to manage mutation carriers (both with and without a concomitant diagnosis of breast cancer), this text provides a comprehensive, state-of-the art review of this field. It represents a valuable resource for a myriad of clinicians and healthcare personnel who interface with these patients. The text discusses the latest recommendations for genetic counseling and risk assessment, provides a framework for considering reducing risk in mutation carriers who do not present with a concomitant diagnosis of breast cancer, and finally elucidates the many considerations of managing a breast cancer patient with a BRCA mutation. The text presents a multidisciplinary approach gleaning insights from imaging, breast surgery, gynecology, plastic surgery, medical oncology, radiation oncology and psycho-oncology.

Managing BRCA Mutation Carriers will be a useful resource for physicians and healthcare providers from a myriad of disciplines who manage BRCA mutation carriers. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.

Contents:

Managing BRCA Mutation Carriers

Anees B. Chagpar

Contents Preface

Chapters

1 Risk Assessment for Breast Cancer

Anvy Nguyen, Jessica Cintolo-Gonzalez, Jennifer K. Plichta, and Kevin S. Hughes

2 Genetic Evaluation for Women at Increased Risk

Karina L. Brierley, Claire L. Healy, and Erin W. Hofstatter

3 Imaging Screening and Surveillance

Ellen Warner

4 Risk Reducing Surgery for BRCA1/2 Genetic Mutation Carriers

Cristina O'Donoghue, Sonia Orcutt, Tuya Pal, and Christine Laronga

5 Prophylactic Oophorectomy for Patients with Germline BRCA Mutations

Dario R. Roque and Don S. Dizon

6 Pathology of BRCA Tumors

Julio A. Ibarra

7 Surgical Management of Breast Cancer in BRCA Mutation Carriers

Patricia A. Cronin and Hiram S. Cody III

8 Medical Management of Breast Cancer in BRCA Mutation Carriers

Soley Bayraktar and Banu K. Arun

9 Radiation Oncology Considerations in the Management of Mutation Carriers with Breast Cancer

Meena S. Moran

10 Fertility Preservation in BRCA Carriers: Special Considerations

Iris G. Insogna, Elizabeth S. Ginsburg and Ann H. Partridge

11 Management of Male BRCA Mutation Carriers

Donna-Marie Manasseh, Ryland J. Gore and Patrick I. Borgen

12 Psychosocial, Ethical and Legal Implications for Mutation Carriers

Jacquelyn M. Powers, Jessica M. Long and Willonie Mendonca