Main description:

Current applications of nanotechnology span from new materials for energy production or conversion (including photovoltaics, fuel cells, etc.), to a variety of consumer products and novel pharmacological formulations, and expand now extensively to biomedical research, medical diagnostics and therapy. In this book, a comprehensive overview of the progress achieved in the development of functional nanoparticles for novel bioanalytical techniques and assays, enhancement
of medical diagnostic imaging, and a variety of cancer treatment therapies is presented, and future trends of nanotechnology applications in these areas are evaluated. Particular emphasis is placed on the functionalization of metal, semiconductor and insulator nanoparticles for targeting cancer
cells, delivering drugs and chemotherapeutic agents, preventing or reducing body inflammation response, averting biofouling and cytotoxicity, and enabling cell membrane crossing. Progress in the development of nanoparticles enhancing the diagnostic imaging is discussed in detail and this includes nanoparticles for Magnetic Resonance Imaging (MRI), Computed Tomography (CT) scan, megasonic imaging, and novel photoacoustic and Raman imaging.

Contents:

Preface ; 1. Persistent Luminescence Nanoparticles for Diagnostics and Imaging ; Thomas Maldiney, Daniel Scherman, and Cyrille Richard ; 2. Long-Circulating Polymeric Drug Nanocarriers ; Wei Wu and Xiqun Jiang ; 3. Targeting Gold Nanoparticles for Cancer Diagnostics and Therapeutics ; Andrew J. Coughlin and Jennifer L. West ; 4. The Application of Peptide Functionalized Gold Nanoparticles ; Tao Li, Xiuxia He, and Zhenxin Wang ; 5. Gold Nanoparticles for the Development of Transdermal Delivery Systems ; Dakrong Pissuwan and Takuro Niidome ; 6. Nanoparticles for Noninvasive Radiofrequency-Induced Cancer ; Hyperthermia ; Stuart J. Corr, Mustafa Raoof, Lon J. Wilson, and Steven A. Curley ; 7. The Design of Hybrid Nanoparticles for Image-Guided Radiotherapy ; Christophe Alric, Rana Bazzi, Francois Lux, Gautier Laurent, Matteo Martini, ; Marie Dutreix, Geraldine Le Duc, Pascal Perriat, Stephane Roux, and ; Olivier Tillement ; 8. Functional Nanoparticle-Based Bioelectronic Devices ; Tadeusz Hepel ; 9. Biological Applications of SERS Using Functional Nanoparticles ; Yasutaka Kitahama, Tamitake Itoh, Prompong Pienpinijtham, Sanong Ekgasit, ; Xiao Xia Han, and Yukihiro Ozaki ; 10. Current Progress on Surface-Enhanced Raman Scattering ; Chemical/Biological Sensing ; Justin L. Abell, Jeremy D. Driskell, Ralph A. Tripp, and Yiping Zhaod ; 11. Molecular Sensing Based on Surface-Enhanced Raman Scattering and ; Optical Fibers ; Xuan Yang, Damon A. Wheeler, Claire Gu, and Jin Z. Zhang