Targeted therapy is one of the most burgeoning areas of development in cancer research. The increased knowledge of tumor formation and growth at the molecular level has generated a broad array of therapeutic options, including potent immune cytotoxic activity, growth factor receptor inhibition, and the selective delivery of toxins, isotopes, and drugs to tumors. This book presents an overview of existing targeted therapies, their relevance and role for specific tumors, and their clinical efficacy and impact on patient care.
Overview of Existing Therapies. Signal Transduction Inhibitors. Cell Cycle Inhibitors. Apoptosis Modulators. Anti-Angiogenic Agents. Antivascular Agents. Anti-Invasive Agents. Telomerase and Telomere Interacting Agents. Targeted Agents At Transversal Mechanisms. Conclusion