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Single-Sided NMR
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MORE ABOUT THIS BOOK

Main description:

The use of conventional nuclear magnetic resonance is limited by

the fact that the object needs to be carried to the NMR equipment

and needs to fit inside large superconducting magnets. Both

limitations are removed by single-sided NMR probes based on open

magnets specially adapted to the object under study. These can be

inexpensive and portable sensors that give access to a large

number of applications inaccessible with using conventional magnet

geometries. Substantial improvements in the magnet design,

detection electronics, and the implementation of suitable

techniques to work in the inhomogeneous magnetic fields of open

magnets have allowed scientists and engineers to measure

relaxation-time distributions, diffusion coefficients, 3D images,

velocity distributions, and even highly resolved NMR spectra in

the stray field of the magnet. This book is the first

comprehensive account describing the key issues to be considered

at the time of designing and building open magnets, and

summarizing the arsenal of pulse sequences available today for

material analysis.


Feature:

First comprehensive account of a new and powerful method of nondestructive testing by single-sided NMR imaging.

The book addresses the large market of magnetic resonance imaging in medicine as well as the smaller market in the applied sciences and in engineering.

Written by international experts in the field.


Back cover:

The use of conventional nuclear magnetic resonance is limited by the fact that the object needs to be carried to the NMR equipment and needs to fit inside large superconducting magnets. Both limitations are removed by single-sided NMR probes based on open magnets specially adapted to the object under study. These can be inexpensive and portable sensors that give access to a large number of applications inaccessible with using conventional magnet geometries. Substantial improvements in the magnet design, detection electronics, and the implementation of suitable techniques to work in the inhomogeneous magnetic fields of open magnets have allowed scientists and engineers to measure relaxation-time distributions, diffusion coefficients, 3D images, velocity distributions, and even highly resolved NMR spectra in the stray field of the magnet. This book is the first comprehensive account describing the key issues to be considered at the time of designing and building open magnets, and summarizing the arsenal of pulse sequences available today for material analysis.


Contents:

- Single sided NMR

- NMR in inhomogeneous fields

- Ex-situ measurement of one- and two-dimensional distribution functions

- Hardware

- Single-sided tomography

- High Resolution NMR in Inhomogeneous Fields

- High-resolution spectroscopy in highly homogeneous stray fields

- Biological Tissue

- Applications in material science and cultural heritage

- Spectrometer Hardware


PRODUCT DETAILS

ISBN-13: 9783642163074
Publisher: Springer (Springer Berlin Heidelberg)
Publication date: January, 2011
Pages: 263

Subcategories: Radiology

MEET THE AUTHOR

Currently an Assistant Editor for the journal Cell, Michaeleen Doucleff obtained her PhD in Chemistry from the University of California, Berkeley while working in the laboratory of David E. Wemmer. Doucleff then became a Nancy Nossal postdoctoral fellow at the National Institute's of Health in the laboratory of G. Marius Clore. Throughout her career, she has used NMR spectroscopy and X-ray crystallography to characterize the structure and dynamics of transcription factors and their interaction with DNA.

Mary Hatcher-Skeers is a Professor of Chemistry in the Joint Science Department of Claremont McKenna, Pitzer and Scripps Colleges in Claremont CA.  She teaches General Chemistry, Biochemistry, Physical Chemistry and NMR Spectroscopy.  Hatcher-Skeers received her PhD in Chemistry from the University of Washington while working in the laboratory of Gary Drobny.  She was then a NIH Post-Doctoral Fellow in the labs of Judith Herzfeld at Brandeis University and Robert Griffin at MIT.  Professor Hatcher-Skeers’ research uses solid-state and solution NMR spectroscopy to investigate the role of DNA structure and dynamics in protein and drug binding.  She has trained over 70 undergraduates in her research lab, a number who have gone on to graduate programs in chemistry and biochemistry.

Nicole Crane, Ph.D. is currently a Scientist at the Naval Medical Research Center in Silver Spring, MD where she is establishing the Regenerative Medicine Department’s Advanced Imaging Program.  Her research focuses on development and utilization of spectroscopic techniques to improve understanding of the wound healing process, particularly in traumatic acute wounds, as well as identifying and quantifying transplant-associated ischemia and reperfusion injury. Her experience as an applied spectroscopist includes applications in forensics, pharmaceuticals, and biomedicine. Dr. Crane has published over fifteen peer-reviewed publications and presented at numerous regional and national scientific meetings. She is also an inventor on two US patents.