eBOOKS BY CATEGORY
Your Account
Signaling Mechanisms Regulating T Cell Diversity and Function
Price
Quantity
£64.16
(To see other currencies, click on price)
PDF
Add to basket  

MORE ABOUT THIS BOOK

Main description:

T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.


Contents:

T cell origins, interactions and roles in adaptive immunity. Mechanisms regulating progression through DN stages. Positive selection. Negative selection. ThPok in cd4/cd8 selection. Directing cells into Gamma/Delta variants. Tregs. iNKT. Early events in T cell receptor engagement. T cell engagement and the Immunological Synapse. Orai1-mediated Ca2+ entry and T cell activation. Transcriptional mechanisms modulating Ca2+ signals during T cell activation. IFNs and Differentiation to Th1 cells.


PRODUCT DETAILS

ISBN-13: 9781498705097
Publisher: Productivity Press
Publication date: September, 2016
Pages: 248

Subcategories: Immunology