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Renal Cell Carcinoma
Clinical Management
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Main description:

Renal Cell Carcinoma: Clinical Management provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in kidney cancer. The volume reviews new data about risk factors for the disease, profiles the new staging system for renal cell carcinoma (RCC), highlights our current understanding of familial syndromes of RCC and their molecular genetics, and provides new perspectives about imaging of renal tumors. For localized disease, a greater appreciation of nephron-sparing approaches and the importance of preservation of renal function is discussed in detail. Advances in surgical techniques are highlighted. For metastatic disease, the molecular biology of kidney cancer is reviewed in a concise and understandable manner, including the data that has fostered novel targeted approaches that have revolutionized management. The several landmark phase III targeted therapy trials published in the last few years are placed in context with respect to current management. Integration of surgery and systemic therapy through cytoreductive and consolidative approaches has yielded provocative data that promises to further advance the field, and major advances in this domain are also be discussed.


Feature:

Comprehensive, state-of-the art review

Provides important advances in  new surgical techniques

Provides advances in systemic treatments


Back cover:

Renal Cell Carcinoma: Clinical Management provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in kidney cancer. The volume reviews new data about risk factors for the disease, profiles the new staging system for renal cell carcinoma (RCC), highlights our current understanding of familial syndromes of RCC and their molecular genetics, and provides new perspectives about imaging of renal tumors. For localized disease, a greater appreciation of nephron-sparing approaches and the importance of preservation of renal function is discussed in detail. Advances in surgical techniques are highlighted. For metastatic disease, the molecular biology of kidney cancer is reviewed in a concise and understandable manner, including the data that has fostered novel targeted approaches that have revolutionized management. The several landmark phase III targeted therapy trials published in the last few years are placed in context with respect to current management.


Contents:

Section I: Localized Disease

1.      Etiology of RCC: Incidence, Demographics, and Environmental Factors

By Frédéric D. Birkhäuser, MD, Nils Kroeger, MD, and Allan J. Pantuck, MD MS FACS

 

2.      Pathology of Renal Cell Carcinoma

By Ming Zhou, MD PhD, Huiying He

 

3.      Familial Renal Cell Carinoma

By Simon P. Kim, MD, MPH,  Bradley C. Leibovich, MD

 

4.      Imaging of Renal Cell Carcinoma

By Andrei S. Purysko, MD, Erick M. Remer MD, Brian R. Herts, MD

 

5.      Prognostic Factors for Localized Renal Cell Carcinoma

By Brian R. Lane, MD, PhD.

 

Section II: Management of  Localized RCC

 

6.      Assessment of Oncologic Risk for Clinical Stage T1 Renal Tumors and the Emerging Role of Renal Mass BiopsyBy Matthew N. Simmons MD PhD,  Steven C. Campbell MD PhD

 

7.      Radical Nephrectomy for Localized Renal Tumors: Oncological and Renal Functional Considerations

By Paul Russo, MD FACS

 

8.      Nephron-Sparing Surgery for Renal Cancer

By Alon Z. Weizer MD, MS, Jeffery S. Montgomery MD, MHSA, Khaled S. Hafez, MD

 

9.      Thermal Ablation

By Surena F. Matin MD FACS, Kamran Ahrar MD

 

10.  Active Surveillance of the Small Renal Mass

By Marc C. Smaldone, MD, Daniel Canter,  MD, Alexander Kutikov, MD,  Robert G. Uzzo, MD FACS

 

Section III: Locally Advanced Disease

 

11.  Locally Advanced Renal Cell Carcinoma

By Stephen H. Culp, MD PhD, Christopher G. Wood, MD FACS

 

12.  Neoadjuvant Targeted Therapy and Consolidative Surgery

By Sean P. Stroup MD. Ithaar H. Derweesh, MD

 

Section IV: Advanced Disease

 

13.  Biology of RCC (VEGF, mTOR, immune aspects)

By Alexandra Arreola, W. Kimryn Rathmell, MD, PhD

 

14.  Prognostic Factors in Advanced Renal Cell Carcinoma 

By Michael M. Vickers MD, Daniel Y. C. Heng MD MPH

 

15.  Integration of Surgery in Metastatic Renal Cancer

By Tom Powles, MBBS MRCP MD,  Axel Bex, MD

 

16.  Immunotherapy for Renal Cell Carcinoma

By Diwakar Davar, MD,  Moon Fenton, MD, Leonard J Appleman, MD, PhD

 

17.  Targeted Therapy: Vascular Endothelial Growth Factor (VEGF) 

By Linda Cerbone MD, Cora N. Sternberg, MD

 

18.  mTOR in Renal cell carcinoma

By Eric Jonasch, MD, Michel Choueiri, MD

 

19.  Palliative and Supportive Care for Renal Cancer

By Armida Parala-Metz MD, Mellar Davis MD


PRODUCT DETAILS

ISBN-13: 9781627030625
Publisher: Springer (Humana Press)
Publication date: September, 2012
Pages: 373

Subcategories: Oncology, Urology