Response-adaptive designs, which aim to reduce the number of patients receiving inferior treatments, are becoming increasingly popular in Phase III clinical trials. Written by leading experts, "Response-Adaptive Designs in Clinical Trials" provides an overview of the growing research in this area. It presents up-to-date methodology, and includes all necessary background material on adaptive clinical trials. Illustrating methods with numerous real-world examples from recent clinical trials, the book offers practical guidelines for applying these methods in the field, includes supporting software available for download, and explores future research directions.
Not yet available