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Neurological Complications of Systemic Cancer and Antineoplastic Therapy
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Main description:

Neurological Complications of Systematic Cancer and Antineoplastic Therapy provides an in-depth review of common manifestations related to neurology that occur in patients with systemic cancer. These include brain metastases, spinal cord compression, cerebrovascular events, and leptomeningeal disease. The book also discusses less common complications such as paraneoplastic disorders and neoplastic plexopathy.


Highlights include:




  • The pathophysiology and molecular biology of cancer and the metastatic phenotype

  • Metastatic spread to cranial and peripheral nerves and brachial and lumbosacral plexuses

  • Metabolic and nutritional disorders

  • CNS infections

  • Neurological complications of immunotherapy and bone marrow transplants


Additional chapters review problems related to each specific tumor type, such as breast, lung, and colorectal, as well as gynecological cancer, genitourinary cancer, and malignant melanoma. The book also discusses neurological complications related to treatments such as radiation and chemotherapy.


Bringing clinical trial knowledge from the bench to the bedside, this volume is an essential reference for the practicing oncologist and neurologist.


Contents:

Biology and pathophysiology of nervous system metastases


Herbert B Newton and Mark G Malkin


Intracranial metastases


Herbert B Newton and Mark G Malkin


Epidural metastasis and spinal cord compression


Nader Pouratian, Mark E Shaffrey, and David Schiff


Leptomeningeal metastasis


Linda D Grossheim and Mark G Malkin


Cranial nerve involvement by metastatic cancer


Paul L Moots


Cancer-related plexopathies


Paul L Moots and Michael Edgeworth


Cerebrovascular complications of malignancy


Joseph Rudolph and Jeffrey M Katz


Metabolic and nutritional nervous system dysfunction in cancer patients


Herbert B Newton


Central nervous system infections in cancer patients


Amy A Pruitt


Diagnosis and treatment of paraneoplastic neurological disorders


Annick Desjardins


Neurological complications of lung cancer


Linda D Grossheim, Mark G Malkin, Suriya A Jayapalan, and John W Henson


Neurological complications of breast cancer


Neil E Anderson


Neurological complications of malignant melanoma


Maciej M Mrugala and John W Henson


Neurological complications of leukemia and lymphoma


Lynne P Taylor


Neurological complications of head and neck cancer


Marta Penas-Prado and Morris D Groves


Neurological complications of gynecological cancers


Susan C Pannullo, Eliana T Muskin, Robert D Zimmerman, and Jennifer A Moliterno


Neurological complications of GI cancers


Larry Junck and Mark M Zalupski


Neurologic complications associated with genitourinary cancer


Samer S Kasbari, Marc S Ernstoff, and Camilo E Fadul


CNS complications of sarcoma


Ed Olson and Jeffrey J Raizer


Neurological complications of multiple myeloma


Nina A Paleologos and Allison L Weathers


Neurologic complications of cancer and its therapy during childhood


Mark T Jennings


Neurological complications of radiotherapy


Jeremy Rudnick and Lauren E Abrey


Neurological complications of chemotherapy


April F Eichler and Patrick Y Wen


Neurological complications of immunotherapy


Florence Laigle-Donadey, Gentian Kaloshi, and Jean-Yves Delattre


Neurological complications of steroids and of supportive care


Willem-Johan van de Beek and Charles J Vecht


Psychiatric aspects of care in the cancer patient


William S Breitbart and Yesne Alici


Chronic cancer pain syndromes and their treatment


Nathan I Cherny


Psychosocial issues


Jane R Schubart, Elana Farace, and Robert Cavaliere


Supportive care


Herbert B Newton and Mark G Malkin


Index


PRODUCT DETAILS

ISBN-13: 9781420020496
Publisher: Taylor & Francis (CRC Press)
Publication date: July, 2010
Pages: 648

Subcategories:

MEET THE AUTHOR

Herbert B. Newton, M.D., is Professor of Neurology, Co-Director, Dardinger Neuro-Oncology Center , Esther Dardinger Endowed Chair in Neuro-Oncology and Director in the Division of Neuro-Oncology at the Ohio State University Medical Center, Columbus, Ohio. Dr. Newton is also an Attending Physician in Neuro-Oncology at The Arthur G. James Cancer Hospital and Solove Research Institute and Staff Physician in the Section of Neurology at the Children's Hospital of Columbus. He is a diplomate of the American Board of Psychiatry and Neurology, a Fellow of the American Academy of Neurology and Royal Society of Medicine, and a member of numerous national and international societies.



Mark G. Malkin M.D., is Chief of the Division of Neuro-oncology in the Department of Neurology, and Professor of Neurology and Neurosurgery at the Medical College of Wisconsin, Milwaukee, Wisconsin. Dr. Malkin is also on the active staff of Froedtert Memorial Lutheran Hospital, where he serves as Co-Chair of the Cancer Committee. He is a Fellow of both the Royal College of Physicians of Canada (Neurology) and the American Academy of Neurology. In 2005 he received the Excellence in Clinical Teaching Award from the Department of Neurology at the Medical College of Wisconsin.