Completely updated with contributions by world leaders in surgery and the surgery specialties, this reference assists surgeons in the diagnosis and treatment of patients by considering disease as a derangement of normal physiology, thus allowing the surgeon to correlate the appropriate use of laboratory and radiologic modalities. Arranged according to specific organ systems, the book is easily accessible and reflects the impact that scientific discoveries and technical advances have had on our understanding of the physiologic processes in surgical patients.
GENERAL CONSIDERATIONS IN THE MANAGEMENT OF SURGICAL PATIENTS. Metabolic Response to Starvation, Stress and Sepsis. Pathophysiology of Fluid and Electrolyte Disorders. Surgical Nutrition.The Immune System and the Immunocompromised Patient. Physiologic Basis of Transplantation. Surgical Infection: Principles of Management and Antibiotic Usage. Hemostasis and Thrombosis in the Surgical Patient. Pathophysiology of Shock. Neoplastic Disease: Pathophysiology and Rationale for Treatment. Physiology of Anesthesia and Pain. Sepsis and the Syndrome of Multiple Organ Failure. Application of Cellular and Molecular Biology to Surgical Care. Physiologic Principles in Preparing Patients for Surgery. THE ALIMENTARY TRACT. Esophagus and Stomach. Physiologic Dysfunction of the Esophagus. Gastric Physiology and Acid-Peptic Disorders. Small and Large Intestine. Physiology of Digestion and Absorption. Intestinal Circulation and Vascular Disorders of the Splanchnic Vascular Bed. Inflammatory Disorders of the Small Bowel and Colon. Liver, Biliary Tract, Pancreas and Spleen. Hepatic Physiology. Portal Hypertension. Calculous Disease of the Gallbladder and Common Bile Duct. Normal Exocrine Function and Inflammatory Diseases of the Pancreas. The Jaundiced Patient. The Spleen. Other Conditions. Gastrointestinal Hemorrhage. Anatomy, Physiology and Differential Diagnosis of Acute Abdominal Pain. Neoplastic Disorders of the Gastrointestinal Tract. Mechanical Disorders of the Stomach, Duodenum, and Intestine. Physiologic Derangements of the Anorectum and the Defecatory Pelvic Floor. Derangements in Gastrointestinal Function Secondary to Previous Surgery. THE CARDIOTHORACIC SYSTEM. Lung. Pathobiology of Surgically Relevant Lung Disease. Heart. Normal Cardiac Function. Heart Failure and Resuscitation. Mechanical Support of the Failing Heart: Current Physiologic Concepts and PART. THE URINARY SYSTEM. Urine Formation: From Normal Physiology to Florid Renal Failure. Urinary Tract Obstruction. Lower Urinary Tract Dysfunction (Neurogenic Bladder). THE CENTRAL AND PERIPHERAL NERVOUS SYSTEM. Pathophysiology and Management of Head Injury. Pathophyiology of Spinal Cord Disruption and Injury. Injuries to Peripheral Nerves. THE PERIPHERAL VASCULAR SYSTEM. Physiology of Arterial, Venous, and Lymphatic Flow. Aorta and Arterial Disease of the Lower Extremity. Cerebrovascular Disease and Upper Extremity Vascular Disease. Venous and Lymphatic Abnormalities of the Limbs. Diseases of the Thoracic Aorta. Secondary Hypertension: Pathophysiology and Operative Treatment. THE ENDOCRINE SYSTEM. Calcium and Phosphorous Metabolism and the Parathyroid Gland. Pituitary Dysfunction. Adrenal Glands. The Thyroid Gland. Endocrine Pancreas. Multiple Endocrine Neoplasia: Types 1 and 2. THE INTEGUMENT AND BODY WALL. The Biology of Wound Healing. Breast: Physiologic Considerations in Normal, Benign and Neoplastic States.Hernias of the Abdominal Wall and its Contents. Pathophysiology of Thermal Injury. SPECIAL PHYSIOLOGIC CONSIDERATIONS. Physiologic Problems in the Pediatric Surgical Patient. Physiologic Considerations in the Elderly Surgical Patient. Surgery for Morbid Obesity