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Mechanisms Linking Aging, Diseases and Biological Age Estimation
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Main description:

This book focuses on four of the hallmarks of aging: aspartic acid racemization, advanced glycation end products, telomere shortening and mitochondrial mutations; describing their role in aging and diseases; and their application to age-at-death estimation in forensic sciences in greater depth, displaying the interconnecting pathways among these processes. An additional chapter related to Epigenetics and its role in aging, diseases, and forensic age estimation is also included. This book is aimed at a broad audience: from students being introduced to aging, diseases, and forensic science research to scientists in biomedicine and forensics complementing their knowledge in their respective fields while also increasing their knowledge in other disciplines.


Contents:

ASPARTIC ACID RACEMIZATION Introduction to Aspartic Acid Racemization Christian Thomas and Sara C. Zapico Aspartic Acid Racemization on Aging Sara C. Zapico, Christian Thomas and Sofia Tirados Menendez Aspartic Acid Racemization and Aging in Cartilaginous Tissue Sarit Sara Sivan, Alice Maroudas and Ellen Wachtel Racemization and Isomerization of Aspartyl Residues in Amyloid Peptides Involved in the Development of Alzheimer's Disease Koichi Inoue and Toshimasa Toyo'oka Aspartic Acid Racemization: Applications to Forensic and Archaeological Age Estimation Rebecca C. Griffin and Matthew Collins ADVANCED GLYCATION ENDPRODUCTS Advanced Glycation Endproducts: An Introduction Andreas Simm and Alexander Navarrete Santos Advanced Glycation and Aging Alejandro Gugliucci AGE-RAGE Axis in the Aging and Diabetic Heart: Prime Target for Adjunctive Therapeutic Intervention Karen M. O'Shea, Ann Marie Schmidt and Ravichandran Ramasamy Advanced Glycation Endproducts in Aging Skin Paraskevi Gkogkolou and Markus Bohm Advanced Glycation Endproducts and Neurological Diseases Teresita Menini Advanced Glycation Endproducts for Age at Death Estimation Luis L. Cabo, Christian Thomas and Sara C. Zapico TELOMERES Introduction to Telomere Biology Celia de Frutos and Pablo Bermejo-Alvarez Role of Telomeres in Aging Christian Thomas and Sara C. Zapico Telomeres and Cardiovascular Disease: Facts, Controversies and Limitations Vicente Andres, Beatriz Dorado and Ioakim Spyridopoulos Telomeres in Cancer Joao Vinagre, Ana Pestana, Manuel Sobrinho-Simoes and Paula Soares Forensic Application of Telomere Shortening in Age-at-death Estimation Joe Adserias-Garriga MITOCHONDRIAL DNA MUTATIONS Introduction to Mitochondria Biology Christian Thomas and Sara C. Zapico Mitochondrial DNA Mutations and Aging Rebecca Stone Gordon and Sara C. Zapico Mitochondrial DNA Mutations and Mitochondrial Diseases Maria Elena Gomez-Gomez Reproductive Approaches to Prevent the Transmission of Mitochondrial Diseases Maria Jesus Sanchez-Calabuig, Noelia Fonseca Balvis, Serafin Perez-Cerezales and Pablo Bermejo-Alvarez Mitochondrial DNA Mutations and Neurodegenerative Diseases Paula Nunez An Overview of mtDNA Analysis for Age-at-death Estimation in Forensic Sciences Silvia Zoppis EPIGENETICS Epigenetics: Its Role in Aging, Diseases and Biological Age Estimation Christian Thomas and Sara C. Zapico


PRODUCT DETAILS

ISBN-13: 9781498709705
Publisher: Productivity Press
Publication date: December, 2016
Pages: 304

Subcategories: Endocrinology, Physiology