This title includes a number of Open Access chapters. This book examines conserved pathways mediating cell cycle progression and cell polarity establishment. It includes examples of yeast, regulatory circuits, and feedback regulation, with emphasis on system-wide approaches. It also covers protein interaction networks and trait locus analysis and presents methods and challenges in comparative genomics analysis and evolutionary genetics.
Introduction Cell Polarity, Growth, and Cell Cycle Daughter-Specific Transcription Factors Regulate Cell Size Control in Budding Yeast, Stefano Di Talia, Hongyin Wang, Jan M. Skotheim, Adam P. Rosebrock, Bruce Futcher, and Frederick R. Cross Modeling Robustness Tradeoffs in Yeast Cell Polarization Induced by Spatial Gradients, Ching-Shan Chou, Qing Nie, and Tau-Mu Yi Multisite Phosphorylation of the Guanine Nucleotide Exchange Factor Cdc24 during Yeast Cell Polarization, Stephanie C. Wai, Scott A. Gerber, and Rong Li Yeast Regulatory Circuits Roles of Candida albicans Gat2, a GATA-Type Zinc Finger Transcription Factor, in Biofilm Formation, Filamentous Growth and Virulence, Han Du, Guobo Guan, Jing Xie, Yuan Sun, Yaojun Tong, Lixin Zhang, and Guanghua Huang Deciphering Human Heat Shock Transcription Factor 1 Regulation via Post-Translational Modification in Yeast, Liliana Batista-Nascimento, Daniel W. Neef, Phillip C. C. Liu, Claudina Rodrigues-Pousada, and Dennis J. Thiele Environmental Regulation of Prions in Yeast, Liming Li and Anthony S. Kowal Heterologous Gln/Asn-Rich Proteins Impede the Propagation of Yeast Prions by Altering Chaperone Availability, Zi Yang, Joo Y. Hong, Irina L. Derkatch, and Susan W. Liebman Gene Expression and Trait Locus Analysis Strategy of Transcription Regulation in the Budding Yeast, Sagi Levy, Jan Ihmels, Miri Carmi, Adina Weinberger, Gilgi Friedlander, and Naama Barkai A Screen for RNA-Binding Proteins in Yeast Indicates Dual Functions for Many Enzymes, Tanja Scherrer, Nitish Mittal, Sarath Chandra Janga, and Andre P. Gerber Genetic Landscape of Open Chromatin in Yeast, Kibaick Lee, Sang Cheol Kim, Inkyung Jung, Kwoneel Kim, Jungmin Seo, Heun-Sik Lee, Gireesh K. Bogu, Dongsup Kim, Sanghyuk Lee, Byungwook Lee, and Jung Kyoon Choi Comparative Genomics High Quality de novo Sequencing and Assembly of the Saccharomyces arboricolus Genome, Gianni Liti, Alex N. Nguyen Ba, Martin Blythe, Carolin A. Muller, Anders Bergstrom, Francisco A. Cubillos, Felix Dafhnis-Calas, Shima Khoshraftar, Sunir Malla, Neel Mehta, Cheuk C. Siow, Jonas Warringer, Alan M. Moses, Edward J. Louis, and Conrad A. Nieduszynski Comparative Gene Expression Between Two Yeast Species, Yuanfang Guan, Maitreya J. Dunham, Olga G. Troyanskaya, and Amy A. Caudy Whole-Genome Comparison Reveals Novel Genetic Elements That Characterize the Genome of Industrial Strains of Saccharomyces cerevisiae, Anthony R. Borneman, Brian A. Desany, David Riches, Jason P. Affourtit, Angus H. Forgan, Isak S. Pretorius, Michael Egholm, and Paul J. Chambers Index