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Inhalation Drug Delivery
Techniques and Products
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Main description:

The lung offers a unique and challenging route for drug administration for the treatment of local respiratory and systemic diseases. Advances in drug product formulation and inhalation device design are creating new opportunities for inhaled drug delivery as an alternative to oral and parenteral routes. However, the process of delivering drugs to the lung is complex and related to factors associated with the inhaled products and the patient.


This book aims to provide a comprehensive and up to date understanding of the processes and mechanisms involved in inhalation drug delivery, with a strong focus on inhalation products, specific equipment and laboratory techniques.


Students studying Pharmacy, Pharmaceutical Science and technology, Medicine or in general Life Science and Technology, at both undergraduate levels, will find this a concise resource, bringing new perspectives from a variety of research field balanced with industrial aspects.


Back cover:

The lung offers a unique and challenging route for drug administration for the treatment of local respiratory and systemic diseases. Advances in drug product formulation and inhalation device design are creating new opportunities for inhaled drug delivery as an alternative to oral and parenteral routes. However, the process of delivering drugs to the lung is complex and related to factors associated with the inhaled products and the patient.


This book aims to provide a comprehensive and up to date understanding of the processes and mechanisms involved in inhalation drug delivery, with a strong focus on inhalation products, specific equipment and laboratory techniques.


Students studying Pharmacy, Pharmaceutical Science and technology, Medicine or in general Life Science and Technology, at both undergraduate levels, will find this a concise resource, bringing new perspectives from a variety of research field balanced with industrial aspects.


Contents:

List of contributors xi


Series foreword xiii


Preface xv


1 Inhalation drug delivery 1
Daniela Traini


2 Inhalation and nasal products 15
Daniela Traini and Paul M. Young


3 Formulation of inhalation medicines 31
Daniela Traini and Paul M. Young


4 Novel particle production technologies for inhalation products 47
Hak–Kim Chan and Philip Chi Lip Kwok


5 Methods for understanding, controlling, predicting, and improving drug product performance 63
David A. V. Morton


6 Aerodynamic assessment for inhalation products: fundamentals and current pharmacopoeial methods 91
Francesca Buttini, Gaia Colombo, Philip Chi Lip Kwok and Wong Tin Wui


7 Proteins, peptides, and controlled–release formulations for inhalation 121
Philip Chi Lip Kwok, Rania Osama Salama and Hak–Kim Chan


8 Pharmaceutical development studies for inhalation products 145
Gaia Colombo, Chiara Parlati and Paola Russo


9 Quality of inhalation products: specifications 169
Paolo Colombo, Francesca Buttini and Wong Tin Wui


Index.


PRODUCT DETAILS

ISBN-13: 9781118397206
Publisher: John Wiley & Sons Ltd (Wiley–Blackwell)
Publication date: January, 2013
Pages: 218

Subcategories: Addictions and Therapy, Pharmacology