This portable and practical handbook, first published in 2006, provides a concise guide to the essentials of pediatric HIV care in a form suitable for doctors in the busy hospital setting. During recent years, many agents for the treatment and prophylaxis of HIV infection and the opportunistic infections that accompany HIV infection have been developed, and many new ways of monitoring HIV infection in children have been produced. These therapies and approaches to management are complicated, but the long-term health of HIV-infected children depends on their correct application. This handbook presents the core information and guidelines necessary for effective management of infected children. Two other important themes are ways to minimise mother-to-infant transmission, and the challenges of looking after these children in resource-poor countries.
Foreword; Preface; Introduction; Part I. Scientific Basis of Pediatric HIV Care: 1. The scientific basis of pediatric HIV care; 2. The epidemiology of pediatric HIV disease/infection; Part II. General Issues in the Care of Pediatric HIV Patients: 3. Diagnosis of HIV infection in children; 4. Prevention of mother-to-child/vertical transmission of HIV; 5. Routine pediatric care; 6. Emergency evaluation and care; 7. Adherence to therapy in pediatric HIV disease or adherence to antiretroviral therapy in children and youth; 8. Adolescents and HIV; 9. Growth, nutrition and metabolism; 10. Neurodevelopmental/neurobehavioral function and assessment of children and adolescents with HIV-1 infection; Part III. Antiretroviral Therapy: 11. Antiretroviral therapy; 12. Antiretroviral drug interactions; 13. Metabolic complications of antiretroviral therapy in children; 14. Assessment and management of resistance to antiretroviral or HIV drug resistance; 15. Initiating and changing antiviral therapy; 16. Therapeutic drug monitoring in pediatric HIV infection; 17. HIV post-exposure prophylaxis for pediatric patients; Part IV. Clinical Manifestations of HIV Infection in Children; 18. Dermatological problems in HIV-infected children or cutaneous diseases; 19. Neurologic problems; 20. Ophthalmologic (Ophthalmic) problems in the HIV-infected child; 21. Oral health and dental problems in the HIV-infected child; 22. Otitis media and sinusitis in patients with HIV infection; 23. Cardiac problems; 24. Pulmonary problems; 25. Hematologic problems: diagnosis and management; 26. Gastrointestinal disorders of HIV disease; 27. Renal disease in or associated with pediatric HIV (or HIV-1) infection; 28. Endocrinologic problems or endocrine disorders; 29. HIV-associated malignancies in children or neoplastic disease in pediatric HIV infection; Part V. Infectious Problems in Pediatric HIV Disease: 30. Typical bacterial infections or serious infections caused by typical bacteria; 31. Mycobacterium tuberculosis or tuberculosis; 32. Atypical mycobacteria or disseminated mycobacterium avium complex infection; 33. Fungal infections in HIV-infected children; 34. Herpesvirus infections; 35. Pneumocystis carinii (PCP); Part VI. Medical Social and Legal Issues: 36. Medical issues related to the care for HIV-infected children in the home, day care, school and community; 37. Contact with social service agencies in pediatric HIV care delivery; 38. Psychosocial factors associated with childhood bereavement and grief; 39. Legal issues for HIV-infected children; Appendices: Formulary/drug ready reference; NIH-sponsored clinical trials for pediatric HIV disease; Online resources; Legal appendix; Index.