Including a chapter by 2014 Nobel laureates May-Britt Moser and Edvard MoserAn unprecedented look at the quest to unravel the mysteries of the human brain, The Future of the Brain takes readers to the absolute frontiers of science. Original essays by leading researchers such as Christof Koch, George Church, Olaf Sporns, and May-Britt and Edvard Moser describe the spectacular technological advances that will enable us to map the more than eighty-five billion neurons in the brain, as well as the challenges that lie ahead in understanding the anticipated deluge of data and the prospects for building working simulations of the human brain. A must-read for anyone trying to understand ambitious new research programs such as the Obama administration's BRAIN Initiative and the European Union's Human Brain Project, The Future of the Brain sheds light on the breathtaking implications of brain science for medicine, psychiatry, and even human consciousness itself.Contributors include: Misha Ahrens, Ned Block, Matteo Carandini, George Church, John Donoghue, Chris Eliasmith, Simon Fisher, Mike Hawrylycz, Sean Hill, Christof Koch, Leah Krubitzer, Michel Maharbiz, Kevin Mitchell, Edvard Moser, May-Britt Moser, David Poeppel, Krishna Shenoy, Olaf Sporns, Anthony Zador.
List of Contributors ixPreface Gary Marcus and Jeremy Freeman xiMAPPING THE BRAINBuilding Atlases of the Brain 3Mike Hawrylycz with Chinh Dang, Christof Koch, and Hongkui ZengWhole Brain Neuroimaging and Virtual Reality 17Misha B. AhrensProject MindScope 25Christof Koch with Clay Reid, Hongkui Zeng, Stefan Mihalas, Mike Hawrylycz, John Philips, Chinh Dang, and Allan JonesThe Connectome as a DNA Sequencing Problem 40Anthony ZadorRosetta Brain 50George Church with Adam Marblestone and Reza KalhorCOMPUTATIONUnderstanding the Cortex through Grid Cells 67May-Britt Moser and Edvard I. MoserRecording from Many Neurons Simultaneously: From Measurement to Meaning 78Krishna V. ShenoyNetwork Neuroscience 90Olaf SpornsLarge-Scale Neuroscience: From Analytics to Insight 100Jeremy FreemanSIMULATING THE BRAINWhole Brain Simulation 111Sean HillBuilding a Behaving Brain 125Chris EliasmithLANGUAGEThe Neurobiology of Language 139David PoeppelTranslating the Genome in Human Neuroscience 149Simon E. FisherColor plates follow p. 160SKEPTICSConsciousness, Big Science, and Conceptual Clarity 161Ned BlockFrom Circuits to Behavior: A Bridge Too Far? 177Matteo CarandiniLessons from Evolution 186Leah KrubitzerLessons from the Genome 194Arthur Caplan with Nathan KunzlerThe Computational Brain 205Gary MarcusIMPLICATIONSNeurotechnology 219John DonoghueThe Miswired Brain, Genes, and Mental Illness 234Kevin J. MitchellNeural Dust: An Untethered Approach to Chronic Brain-Machine Interfaces 243Michel M. Maharbiz with Dongjin Seo, Jose M. Carmena, Jan M. Rabaey, and Elad AlonAFTERWORDNeuroscience in 2064: A Look at the Last Century 255Christof Koch and Gary MarcusGlossary 271Index 275