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Effects of Persistent and Bioactive Organic Pollutants on Human Health
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Main description:

Examines what we know about the relationship between organicchemicals and human disease


Organic chemicals are everywhere: in the air we breathe, thewater we drink, and the food we eat. They are also found in amyriad of common household and personal care products.Unfortunately, exposure to some organic chemicals can result inadverse health effects, from growth and developmental disorders tocancer and neurodegenerative diseases. This book examines howorganic chemicals affect human health. It looks at the differentdiseases as well as how individual organ systems are affected byorganic chemicals.


Effects of Persistent and Bioactive Organic Pollutants onHuman Health begins with an introductory chapter explaining whywe should care about organic chemicals and their effect on humanhealth. Next, the authors address such important topics as:



  • Burden of cancer from organic chemicals

  • Organic chemicals and obesity

  • Effects of organic chemicals on the male reproductivesystem

  • Organic chemicals and the immune system

  • Intellectual developmental disability syndromes and organicchemicals

  • Mental illness and exposure to organic chemicals


The book ends with an assessment of how much human disease iscaused by organic chemicals. Chapters have been contributed byleading international experts in public and environmental healthand are based on the latest research findings. Readers will findthat all of the contributions are clear and easy to comprehend,with extensive references for further investigation of individualtopics.


Effects of Persistent and Bioactive Organic Pollutants onHuman Health is recommended for students and professionals inmedicine as well as public and environmental health, bringing themfully up to date with what we know about the relationship betweenorganic chemicals and human health.


Back cover:

Examines what we know about the relationship between organicchemicals and human disease


Organic chemicals are everywhere: in the air we breathe, thewater we drink, and the food we eat. They are also found in amyriad of common household and personal care products.Unfortunately, exposure to some organic chemicals can result inadverse health effects, from growth and developmental disorders tocancer and neurodegenerative diseases. This book examines howorganic chemicals affect human health. It looks at the differentdiseases as well as how individual organ systems are affected byorganic chemicals.


Effects of Persistent and Bioactive Organic Pollutants onHuman Health begins with an introductory chapter explaining whywe should care about organic chemicals and their effect on humanhealth. Next, the authors address such important topics as:



  • Burden of cancer from organic chemicals

  • Organic chemicals and obesity

  • Effects of organic chemicals on the male reproductivesystem

  • Organic chemicals and the immune system

  • Intellectual developmental disability syndromes and organicchemicals

  • Mental illness and exposure to organic chemicals


The book ends with an assessment of how much human disease iscaused by organic chemicals. Chapters have been contributed byleading international experts in public and environmental healthand are based on the latest research findings. Readers will findthat all of the contributions are clear and easy to comprehend,with extensive references for further investigation of individualtopics.


Effects of Persistent and Bioactive Organic Pollutants onHuman Health is recommended for students and professionals inmedicine as well as public and environmental health, bringing themfully up to date with what we know about the relationship betweenorganic chemicals and human health.


Contents:

Contributors vii


1. Introduction: Why Should We Care about Organic Chemicalsand Human Health? 1
David O. Carpenter


2. Sources of Human Exposure 8
Martí Nadal and José L. Domingo


3. The Burden of Cancer from Organic Chemicals 26
Molly M. Jacobs, Rachel I. Massey, and Richard W. Clapp


4. Carcinogenicity and Mechanisms of Persistent OrganicPollutants 57
Gabriele Ludewig, Larry W. Robertson, and Howard P.Glauert


5. Diabetes and the Metabolic Syndrome 101
Duk–Hee Lee and David R. Jacobs, Jr.


6. Mechanistic Basis for Elevation in Risk of Diabetes Causedby Persistent Organic Pollutants 130
Jérôme Ruzzin


7. Cardiovascular Disease and Hypertension 143
Marian Pavuk and Nina Dutton


8. Obesity 174
Eveline Dirinck, Adrian Covaci, Luc Van Gaal, and StijnVerhulst


9. Effects and Predicted Consequences of Persistent andBioactive Organic Pollutants on Thyroid Function 203
Stefanie Giera and R. Thomas Zoeller


10. An Overview of the Effects of Organic Compounds onWomen s Reproductive Health and Birth Outcomes 237
Susan R. Reutman and Juliana W. Meadows


11. Effects of Organic Chemicals on the Male ReproductiveSystem 315
Lars Rylander and Anna Rignell–Hydbom


12. Effects of Endocrine–Disrupting Substances on Bone andJoint 332
Chi–Hsien Chen and Yueliang Leon Guo


13. Organic Chemicals and the Immune System 362
David O. Carpenter


14. Exposures to Organic Pollutants and Respiratory Illnessesin Adults and Children 384
Krassi Rumchev, Jeff Spickett, and Janelle Graham


15. Cognitive Function 400
Lizbeth López–Carrillo and Mariano E. Cebrián


16. Intellectual Developmental Disability Syndromes andOrganic Chemicals 421
David O. Carpenter


17. Mechanisms of the Neurotoxic Actions of Organic Chemicals448
David O. Carpenter


18. Parkinson s Disease 471
Samuel M. Goldman


19. Psychiatric Effects of Organic Chemical Exposure514
James S. Brown, Jr.


20. Growth and Development 532
Lawrence M. Schell, Mia V. Gallo, and Kristopher K.Burnitz


21. How Much Human Disease Is Caused by Exposure to OrganicChemicals? 557
David O. Carpenter


Index 570


PRODUCT DETAILS

ISBN-13: 9781118679548
Publisher: John Wiley & Sons Ltd (Wiley–Blackwell)
Publication date: October, 2013
Pages: 608
Dimensions: 150.00 x 243.00 x 35.59

Subcategories: Public Health

MEET THE AUTHOR

DAVID O. CARPENTER, MD, is a public health physician. His research focuses on human diseases resulting from exposure to environmental contaminants. Following positions at the National Institute of Mental Health and the Armed Forces Radiobiology Research Institute, Dr. Carpenter joined the New York State Department of Health as Director of the Wadsworth Center for Laboratories and Research. He helped create and became the first Dean of the School of Public Health, a collaborative endeavor of the University at Albany (SUNY) and the New York State Department of Health. Upon stepping down as Dean, Dr. Carpenter founded the Institute for Health and the Environment. In 2011, the Institute was named a Collaborating Centre of the World Health Organization in Environmental Health.