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Deep Brain Stimulation
Indications and Applications
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Main description:

Drawing on the extensive clinical and research expertise of the Mayo Clinic Neural Engineering Laboratory, USA, led by Kendall H. Lee, MD, PhD, this book addresses the history of therapeutic electrical stimulation of the brain, its current application and outcomes, as well as theories about its underlying mechanisms. It reviews cutting-edge research on measures of local stimulation-evoked neurochemical release, latest imaging research on stimulation-induced neural circuitry activation, and the state of the art on closed-loop feedback devices for stimulation delivery.


Introduction to Deep Brain Stimulation. Overview of the History and Application of Deep Brain Stimulation. Biophysical Fundamentals of Neural Excitation. Motor Circuit Activity in Parkinson's Disease. Neuroimaging in Deep Brain Stimulation. Ethical Considerations in the Use of Deep Brain Stimulation. Clinical Applications. Deep Brain Stimulation for Parkinson's Disease. Deep Brain Stimulation for Tremor. Deep Brain Stimulation for Dystonia. Deep Brain Stimulation for Obsessive-Compulsive Disorder. Deep Brain Stimulation for Tourette Syndrome. Deep Brain Stimulation for Treatment-Resistant Depression. Deep Brain Stimulation for Chronic Pain. Deep Brain Stimulation for Medically Refractory Epilepsy. Deep Brain Stimulation for Memory Dysfunction. Deep Brain Stimulation for Cluster Headache. Functional Electrical Stimulation for Spinal Cord Injury. Research on Mechanisms of DBS and Neuromodulation. Theories of Deep Brain Stimulation Mechanisms. The Role of Astrocytes in Deep Brain Stimulation. Electrochemical Measurements of Neurochemical Concentration. Electrodes for Neural Stimulation and Monitoring. Closed-Loop Control Systems for Deep Brain Stimulation Therapy. Molecular and Cellular Neuromodulation for Central Nervous System Injury.


ISBN-13: 9781315341095
Publisher: Pan Stanford Publishing Pte Ltd
Publication date: December, 2016
Pages: 600

Subcategories: Neurology, Neuroscience, Neurosurgery