Pain is one of the most common symptoms of neurological disease and its appropriate management is essential to the effective care of patients. Neurological disorders differ in their specific pain phenotype, mechanisms and therapy. Case Studies in Neurological Pain addresses the specific pain issues, treatment and pathophysiology in patients with a wide spectrum of neurological disease. Clinical case studies have long been recognized as a useful adjunct to problem-based learning and continuing professional development. They emphasize the need for clinical reasoning, integrative thinking, problem-solving, communication, teamwork and self-directed learning – all desirable generic skills for health care professionals. Presenting real-life cases – covering conditions including diabetic and idiopathic polyneuropathies, focal neuropathies, multiple sclerosis and headache disorders – this book provides neurologists, neurosurgeons, pain clinic specialists and primary care physicians with an understanding of problems encountered in neurological practice. There are also chapters on mechanisms of neurological pain and new treatment guidelines.
Preface; Part I. The Biology of Neuropathic Pain: 1. Mechanisms of neuropathic pain; Part II. Focal, or Localized Neuropathies: 2. Pain in carpal tunnel syndrome; 3. Pain and cervical radiculopathy; 4. Pain and diabetic lumbosacral plexopathy; 5. Pain and meralgia paraesthetica; 6. Pain and lyme radiculopathy (Borrelia-associated radiculitis); 7. Neuralgic amyotrophy; 8. Painful radiculopathy associated with herpes zoster infection; Part III. Generalized neuropathies or polyneuropathies: 9. Pain and chronic inflammatory demyelinating polyneuropathy; 10. Pain and diabetic polyneuropathy (DPN); 11. Painful idiopathic polyneuropathy; 12. Pain in vasculitic neuropathy; 13. Painful polyneuropathy associated with anti-MAG autoantibodies; 14. Painful polyneuropathy associated with inherited amyloidosis; 15. Small fiber neuropathy in sarcoidosis; 16. Pain and small fiber polyneuropathy in Fabry disease; Part IV. Other Neuromuscular and Neurological Disorders: 17. Pain and proximal myotonic myopathy (DM2); 18. Complex regional pain syndrome; 19. Pain and polymyalgia rheumatica; 20. Phantom pain; Part V. CNS Disorders: 21. Pain in Parkinson's disease; 22. Pain associated with amyotrophic lateral sclerosis (ALS); 23. Pain in Brown–Séquard syndrome; 24. Pain in syringomyelia; 25. Central pain with thalamic infarct; 26. Pain in multiple sclerosis; Part VI. Headache Disorders: 27. Chronic migraine; 28. Cluster headache; 29. Paroxysmal hemicrania; 30. Trigeminal neuralgia; 31. Headache and acute cerebral ischemia; Part VII. Treatment: 32. Therapeutics in neuropathic pain; Index.