Developments in mesoporous ceramics in drug delivery, nanomedicine, and bone tissue regeneration have opened promising developments in biomedical research, many applicable in the clinic in the near future. Due to the ability to fine-tune the physicochemical properties of these materials, the field has experienced an impressive burst in the number of publications. As controlled drug delivery systems are one of the most promising applications for human health care, it is now necessary to set the milestones of this technology, from the very basic to the most advanced. Biomedical Applications of Mesoporous Ceramics: Drug Delivery, Smart Materials and Bone Tissue Engineering is a comprehensive overview of silica-based mesoporous materials with special attention given to their use in drug delivery systems, sophisticated stimuli-responsive materials, and bone tissue engineering. The book provides a comprehensive overview of the basic aspects of the properties of mesoporous materials, with a focus on textural properties such as surface and porosity.
Starting from this consolidated knowledge, it then addresses various aspects of more sophisticated stimuli-responsive materials and bone tissue engineering, detailing the research and development of these biomedical applications.
Biocompatible and Bioactive Mesoporous Ceramics General Properties of Ordered Mesoporous Ceramics Biodegradable and Bioactive Ceramics Calcium Phosphates Silica Organic Functionalization of Ordered Mesoporous Ceramics In Vitro Studies In Vivo Studies Mesoporous Ceramics as Drug Delivery Systems Adsorption of Biomolecules Release of Biomolecules Oral Drug Delivery Topical and Transdermal Drug Delivery Local Drug Delivery Targeted Drug Delivery Stimuli-Responsive Drug Delivery Systems Based on Mesoporous Silica pH as Release Trigger Temperature as Release Trigger Redox Potential as Release Trigger Light as Release Trigger Magnetic Field as Release Trigger Ultrasounds as Release Trigger Enzymes as Release Triggers Antigens as Release Triggers Aptamer Target as Release Trigger Dual Stimuli as Release Trigger Mesoporous Silica Nanoparticles in Nanomedicine Drug Delivery Targeting Gene Therapy Imaging Hyperthermia-Based Therapy Biosensing Theranostic Nanomedicine Biocompatibility and Toxicity Bone Tissue Regeneration Tissue Engineering Bone Tissue Engineering Biocompatibility of Ordered Mesoporous Silica