The ability to regulate and manipulate the generation or remodeling of blood vessels is key to the successful treatment of many chronic diseases, both oncological and non-oncological. Several bioactive compounds present in human diets are now known to exert an inhibitive effect on the either the signaling or construction of new blood vessels. The identification and characterization of these anti-angiogenic molecules opens a new avenue for the research and production of functional and medicinal foods with far reaching implications for the food-based treatment of chronic degenerative disease. Drawing from an extensive list of esteemed international contributors, "Anti-Angiogenic Functional and Medicinal Foods" explores the history and scope of the use of conventional foods, nutraceuticals, and health products in North America, Europe, the Middle East, Asia, India, Australia, and New Zealand.The text illustrates the importance of recent 'omics' technology and its implication on our understanding of nutrition and systemic function.
Recent advancements in proteomics, genomics, and toxicogenomics give us a far more detailed picture of the molecular basis of nutrition and systems toxicology than we have had in the past. Explaining the role of angiogenesis in various chronic diseases, individual chapters consider endothelial cell responses, the mechanism of the angiogenic cascade, and the angiogenic function involved in tumors, cardiovascular disease, inflammatory arthritis, and obesity. A collection of chapters studies specific foods and their functional bioactive compounds such as the effects of edible berry anthocyanins, various Chinese medicinal foods, dietary flavanoids, probiotics, shark cartilage, EPA and DHA, and marine polysaccharides.This book concludes with a discussion of the challenges faced during the development and delivery of anti-angiogenic functional food products. Presenting the current research and state of the science, "Anti-Angiogenic Functional and Medicinal Foods" provides researchers, scientists, clinical nutritionists, and oncologists with a valuable reference to this important and growing mode of therapy.
History and Scope of Functional Foods Around the World Scope of Conventional and Functional Foods in the U.S.A., J.N. Losso Functional Foods, Nutraceuticals and Natural Health Products in Canada, K. Fitzpatrick and F.Shahidi History and Scope of Functional Foods in Japan, M. Shimizu and A. Kawakami Functional Foods in India: History and Scope, T.P. Devasagayam, J.C. Tilak, and R. Singhal History and Scope of Functional Foods in China, A. Woo, Y. Zhao, R. Zhang, C. Zhou,and C. Cheng History and Current Status of Functional Foods in Korea, H. Joo Lee and Y.J. Surh Australia and New Zealand, H. Singh, L. Tapsell, M. Gidley, P. Gopal,and P.J. Moughan Prophylactic Phenolic Antioxidants in Functional Foods of Tropical Island States of the Mascarene Archipelago (Indian Ocean), T. Bahorun, V.S. Neergheen, M.A. Soobrattee, V.A. Luximon-Ramma,and O.I. Aruoma Functional Foods in Mediterranean and Middle Eastern Countries: History, Scope and Dietary Habits, F. Yildiz, P. Kotzekidou, A. Michaelidou,and G. Nocella Functional Foods in the European Union, A. Palou, P. Oliver, A. Ma Rodriguez, and A. Caimari Functional Foods in the European Union: Main Issues and Impact on the Food Industry, M. Canavari, A. Castellini, G. Nocella,and C. Pirazzoli Functional Foods Legislation in Brazil, F.M. Lajolo and E. Miyazaki The "Ohmics" Technologies and Functional Foods Principles of Proteomics, L. Jin, L. Rodicio, and P.A. Limbach Toxicogenomics and Systems Toxicology, M.D. Waters and J.M. Fostel Angiogenesis and Chronic Degenerative Diseases Endothelial Cell Responses to Physiological and Pathophysiological Environments, R. W. Siggins and C. A. Hornick Angiogenic Switch: Roles of Estrogenic Compounds, S.K. Banerjee, G. Ray, P. Van Veldhuizen,and S. Banerjee Reactive Oxygen Species and Angiogenesis, S. Chatterjee Angiogenesis in Inflammatory Arthritis, S. Mandal, S. Kana kundu-Raychaudhuri,and S. P. Raychaudhuri Angiogenesis and Cardiovascular Diseases, R.J. Tomanek Angiogenesis and Anti-Angiogenesis in Brain Tumors, R.H. Goldbrunner Diabetes and Angiogenesis, G. Trimurtulu, S.Venkateswarlu, and G.V. Subbaraju Obesity and Angiogenesis, D. Bagchi, S. Zafra-Stone, C.K. Sen, and M. Bagchi Angiogenesis, Functional, and Medicinal Foods Screening Functional Foods as Inhibitors of Angiogenesis Biomarkers, J.N. Losso Role of Edible Berry Anthocyanins in Angiogenesis, M. Bagchi, S. Zafra-Stone, J.N. Losso, C.K. Sen,S. Roy, S. Hazra, and D. Bagchi Redox Regulation of Angiogenesis: Anti-Angiogenic Properties of Edible Berries and Its Significance in a Clinical Setting, G.M. Gordillo, D. Bagchi, and C.K. Sen A Novel Nutrient Mixture Containing Ascorbic Acid, Lysine, Proline, and Green Tea Extract Inhibits Critical Parameters in Angiogenesis, M. Waheed Roomi, V. Ivanov, T. Kalinovsky, A. Niedzwiecki,and M. Rath Angiogenesis and Chinese Medicinal Foods, A.Woo, Y. Zhao, R. Zhang, C. Zhou,and C. Cheng Disposition and Metabolism of Dietary Flavonoids, M.J. Kang and D.H. Kim Functional Foods: Probiotics, M. Saarela Potential Anti-Cancer Effects of Shark Cartilage, K.Sato, M.Suganuma, and K. Shichinohe Physiological Effects of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) - A Review, N. Bhaskar and K. Miyashita Marine Polysaccharides and Angiogenesis: Modulation of Angiogenesis by Fucoidans, S. Soeda, S. Koyanagi, and H. Shimeno Development and Delivery of Anti-Angiogenic Functional Food Products: Opportunities and Challenges, J.N. Losso Index