Recently, the implication of biocompatible nanotechnologies has set the stage for an evolutionary leap in diagnostic imaging and therapy. In this scope, the book presents a comprehensive overview of the possible causes, diagnostic criteria, and treatment assessments of amyotrophic lateral sclerosis, and presents the recent findings using innovative, highly sensitive, and novel diagnostic molecular imaging approaches. In addition, the book offers new perspectives of an innovative and recently developed approach in neuroimaging using surface-enhanced nanoimaging microscopy, which can be a promising technique for early diagnosis and treatment assessments.
Clinical Features of Amyotrophic Lateral Sclerosis What Is Amyotrophic Lateral Sclerosis? ALS Signs and Symptoms The Different Types of ALS ALS: Clinical Case Studies Environmental Factors What Environmental Factors Are Suspect in ALS? Toxic Metals and Solvents The Possible Effects of Exercise or Pesticides Environmental Influences of Viruses BMAA Neurotoxic Effects Are Toxins in Seafood Causing ALS? Diagnostic Criteria of Amyotrophic Lateral Sclerosis Steps in the Diagnosis of ALS Electrophysiology in the Revised EEC Nerve Conduction Studies Clinical Features in the Diagnosis of ALS Inconsistent Clinical Features ALS Electrophysiological Features ALS Neuroimaging Features Perspectives of Neuronanomedicine Nanomedicine and Neurological Disorders CNS Neuroprotective Potentials Nanocarriers and CNS-Targeted Drug Delivery Applications Based on Cell-Mediated Drug Delivery CNS Nano-Based Diagnostic Approaches Inflammation and Neurodegeneration: CanWe Measure Neuroprotection and Repair through Imaging Techniques? Constraints in the Treatment of Neurodegenerative Diseases: Future Directions Novel Therapeutic Approaches Conventional Treatments for ALS Occupational Therapy and Supportive Therapy Cell Replacement Therapy and Future Challenges Stem Cell Transplantation Therapy Clinical Applications of Cell Transplant Therapy Trials of Other Cell Sources for Stem Cell Therapy Stem Cell Therapy: Clinical Trials Induced Pluripotent Stem (iPS) Cell Therapy Gene Therapy and Future Challenges