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Allergy and Allergic Diseases
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Main description:

Allergy and Allergic Diseases is an outstanding reference source on all aspects of allergy and allergic diseases. Covering virtually every allergic condition, from the immunological and molecular basis of the allergic response to future trends in allergic disease prevention, this new international editorial team lead by Professor Kay, have completely revised and updated the text, from both a scientific and clinical perspective.




The two volume second edition consists of more than 1800 pages contained in 98 chapters. The first volume covers growing areas on the immunological basis of allergy, particularly regulatory T cells, environmental factors in IgE production and innate immunity, as well as up to date accounts of the cells and mediators of allergic inflammation. The sections on pharmacology, physiology, allergens and animals models have also been fully revised. Volume 2 , the clinical section, contains detailed accounts of allergic conjunctivo–rhinitis, asthma, eosinophilic disorders, allergy and the skin, anaphylaxis, food and drug allergy and allergy prevention. Current approaches to treatment are addressed with emphasis on internationally agreed guidelines; there is a substantial section on allergen immunotherapy, including recent advances.


The price includes a fully searchable CD ROM of the text and a database of 100 colour images.




References were added to the text up until the book went to press, making this the most up–to–date book available in the field.


Back cover:

Allergy and Allergic Diseases is an outstanding reference source on all aspects of allergy and allergic diseases. Covering virtually every allergic condition, from the immunological and molecular basis of the allergic response to future trends in allergic disease prevention, this new international editorial team lead by Professor Kay, have completely revised and updated the text, from both a scientific and clinical perspective.




The two volume second edition consists of more than 1800 pages contained in 98 chapters. The first volume covers growing areas on the immunological basis of allergy, particularly regulatory T cells, environmental factors in IgE production and innate immunity, as well as up to date accounts of the cells and mediators of allergic inflammation. The sections on pharmacology, physiology, allergens and animals models have also been fully revised. Volume 2 , the clinical section, contains detailed accounts of allergic conjunctivo–rhinitis, asthma, eosinophilic disorders, allergy and the skin, anaphylaxis, food and drug allergy and allergy prevention. Current approaches to treatment are addressed with emphasis on internationally agreed guidelines; there is a substantial section on allergen immunotherapy, including recent advances.


The price includes a fully searchable CD ROM of the text and a database of 100 colour images.




References were added to the text up until the book went to press, making this the most up–to–date book available in the field.


Contents:

List of Contributors ix


Foreword xvii


Preface xviii


VOLUME 1 The Scientific Basis of Allergy


Part 1 Immunology of the Allergic Response


1 Allergy and Hypersensitivity: History and Concepts 3
A. Barry Kay


2 Development of Allergy and Atopy 23
Catherine Thornton and Patrick G. Holt


3 T Cells and Cytokines in Asthma and Allergic Inflammation 48
Chris Corrigan


4 Regulatory T Cells and Other Tolerogenic Mechanisms in Allergy and Asthma 83
Catherine Hawrylowicz and Cezmi A. Akdis


5 IgE and IgE Receptors 103
Brian J. Sutton, Andrew J. Beavil, Rebecca L. Beavil, and James Hunt


6 Immunoglobulin Gene Organization and Expression and Regulation of IgE 119
Hannah J. Gould and David J. Fear


7 Environmental Factors in IgE Production 141
Anne Tsicopoulos, Catherine Duez, and Andrew Saxon


8 Antigen–presenting Dendritic Cells and Macrophages 166
Bart N. Lambrecht and Hamida Hammad


9 Innate Immunity in Allergic Disease 187
Ian Sabroe


10 Signal Transduction in Allergic and Inflammatory Cells 203
Rafeul Alam


Part 2 Inflammatory Cells and Mediators


11 Mast Cells: Biological Properties and Role in Health and Allergic Diseases 217
Peter Bradding and Glenn Cruse


12 Eosinophils: Biological Properties and Role in Health and Disease 258
Simon P. Hogan, Helene F. Rosenberg, Redwan Moqbel, Simon Phipps, Paul S. Foster, Paige Lacy, A. Barry Kay, and Marc E. Rothenberg


13 Neutrophils: Biological Properties and Role in Health and Allergic Diseases 295
Alison M. Condliffe, Andrew S. Cowburn, and Edwin R. Chilvers


14 Basophils: Biological Properties and Role in Allergic Diseases 320
Gianni Marone, Giuseppe Spadaro, and Arturo Genovese


15 Leukocyte Adhesion in Allergic Inflammation 337
Michelle J. Muessel and Andrew J. Wardlaw


16 Airway Epithelium 366
Pedro C. Avila and Robert P. Schleimer


17 Airway Vascularity in Asthma 398
John W. Wilson


18 Fibroblasts and the Extracellular Matrix 412
Lynne A. Murray, William G. Glass, Anuk M. Das, and Geoffrey J. Laurent


19 Immune Complexes and Complement: Their Role in Host Defense and in Disease 436
Michael M. Frank and C. Garren Hester


20 Bradykinin Pathways and Allergic Disease 451
Allen P. Kaplan


21 Chemokines 471
James E. Pease and Timothy J. Williams


22 Neurotrophins 494
Wolfgang A. Nockher, Sanchaita Sonar, and Harald Renz


23 Neuropeptides 511
David A. Groneberg and Axel Fischer


24 Late–phase Allergic Reactions in Humans 524
Yee–Ean Ong and A. Barry Kay


Part 3 Pharmacology


25 Antihistamines 551
F. Estelle, R. Simons, and Keith J. Simons


26 Lipid Mediators: Leukotrienes Prostanoids Lipoxins and Platelet–activating Factor 566
Sophie P. Farooque, Jonathan P. Arm, and Tak H. Lee


27 Theophylline and Isoenzyme–selective Phosphodiesterase Inhibitors 634
Mark A. Giembycz


28 Adrenergic Agonists and Antagonists 668
Tony R. Bai


29 Cholinergic Antagonists 683
Nicholas J. Gross


30 Antileukotriene Agents 694
Graeme P. Currie and Brian J. Lipworth


31 Glucocorticosteroids 715
Peter J. Barnes


32 Immunomodulating Drugs 732
Iain A.M. MacPhee


Part 4 Physiology


33 Physiologic Aspects of Asthma 749
Philip W. Ind and Neil B. Pride


34 Aerosol Delivery Systems 768
Thomas G. O Riordan and Gerald C. Smaldone


35 Bronchial Hyperresponsiveness 783
Guy F. Joos


36 Exercise–induced Bronchoconstriction: Animal Models 794
Arthur N. Freed and Sandra D. Anderson


37 Exercise–induced Bronchoconstriction: Human Models 808
Arthur N. Freed and Sandra D. Anderson


38 Sensory and Autonomic Nervous System in Asthma and Rhinitis 823
Bradley J. Undem and Kevin Kwong


39 Mucus and Mucociliary Clearance in Asthma and Allergic Rhinitis 840
Duncan F. Rogers


40 Biology of Vascular Permeability 857
Peter Clark


41 Airway Smooth Muscle 874
Stuart J. Hirst


Part 5 Allergens


42 Biochemistry of Allergens and Recombinant Allergens 895
Rudolf Valenta


43 Host Responses to Allergens 913
Wayne R. Thomas and Belinda J. Hales


44 Allergen Extracts and Standardization 928
Ronald van Ree


45 Grass Tree and Weed Pollen 942
Jean Emberlin


46 Fungi as Allergens 963
Cathryn C. Hassett, W. Elliott Horner, Estelle Levetin, Laurianne G. Wild, W. Edward Davis, Samuel B. Lehrer, and John Lacey


47 Dust Mites and Asthma 984
Thomas A.E. Platts–Mills and Judith A. Woodfolk


48 Animal Allergens 997
Adnan Custovic and Angela Simpson


49 Airborne Allergens and Irritants in the Workplace 1017
Xaver Baur


50 Allergens from Stinging Insects: Ants Bees and Vespids 1123
Te Piao King and Rafael I. Monsalve


51 Cockroach Allergens Environmental Exposure and Asthma 1131
Martin D. Chapman and Anna Pomés


52 Food Allergens 1146
Ricki M. Helm and A. Wesley Burks


53 Latex Allergy 1164
Robyn E. O Hehir, Michael F. Sutherland, Alexander C. Drew, and Jennifer M. Rolland


Part 6 Animal Models of Asthma


54 Primate Models of Allergic Asthma 1187
Charles G. Plopper, Suzette M. Smiley–Jewell, Lisa A. Miller, Michelle V. Fanucchi, Michael J. Evans, Alan R. Buckpitt, Mark V. Avdalovic, Laurel J. Gershwin, Jesse P. Joad, Radhika Kajekar, Shawnessy D. Larson, Kent E. Pinkerton, Laura S. Van Winkle, Edward S. Schelegle, Emily M. Pieczarka, Reen Wu, and Dallas M. Hyde


55 Airway Remodeling in Small Animal Models 1202
Clare M. Lloyd


56 Are Animal Models of Asthma Useful? 1214
Reinhard Pabst


Index


VOLUME 2 Allergic Diseases: Etiology Diagnosis and Treatment


Part 7 Etiology and Pathology


57 Genetics of Asthma and Atopic Dermatitis 1225
Saffron A.G. Willis–Owen, Miriam F. Moffatt, and William O.C. Cookson


58 Epidemiology of Asthma Atopy and Atopic Disease 1239
Debbie L. Jarvis, Seif O. Shaheen, and Peter Burney


59 The Allergy March 1259
Ulrich Wahn


60 Outdoor Air Pollution and Allergic Airway Disease 1266
Gennaro D Amato


61 Indoor Air Pollution 1279
Paul Harrison, Rebecca Slack, and Sanjeev Bagga


62 Molecular Immunopathology of Allergic Disease 1290
Susan Foley and Qutayba Hamid


Part 8 Diagnosis of Allergic Disease


63 Principles and Practice of Diagnosis and Treatment of Allergic Disease 1321
Anthony J. Frew and A. Barry Kay


64 Skin Testing in Diagnosis and Management of Respiratory Allergic Diseases 1335
Pascal Demoly, Anaïs Pipet, and Jean Bousquet


65 Allergy Testing in the Laboratory 1346
Steven O. Stapel and Jörg Kleine–Tebbe


66 Measurement of Markers of Inflammation in Induced Sputum and Exhaled Air 1368
Ian D. Pavord and Dominick E. Shaw


Part 9 Allergic Rhinoconjunctivitis and Immunotherapy


67 Definition and Classification of Allergic Rhinitis and Upper Airways Diseases 1383
Wytske Fokkens and Jean Bousquet


68 Pathophysiology of Allergic Rhinitis 1402
Peter H. Howarth


69 Management and Treatment of Allergic Rhinitis 1430
Jean Bousquet and Michael A. Kaliner


70 Nasal Polyps and Rhinosinusitis 1454
Wouter Huvenne, Paul Van Cauwenberge, and Claus Bachert


71 Ocular Allergy 1482
Avinash Gurbaxani, Virginia L. Calder, and Susan Lightman


72 Mechanisms in Allergen Injection Immunotherapy 1510
Stephen J. Till and Stephen R. Durham


73 Allergen Injection Immunotherapy: Indications and Practice 1522
Hans–Jørgen Malling


74 Sublingual Immunotherapy 1543
G. Walter Canonica and Giovanni Passalacqua


75 Novel Approaches to Allergen Immunotherapy 1555
Mark Larché


Part 10 Asthma and its Treatment


76 Definition Clinical Features Investigations and Differential Diagnosis of Asthma 1567
Piero Maestrelli, Gaetano Caramori, Francesca Franco, and Leonardo M. Fabbri


77 Asthma in Infancy and Childhood 1591
John O. Warner


78 Pathogenesis of Asthma 1608
Stephen T. Holgate


79 Pathology of Asthma 1632
Peter K. Jeffery, A. Barry Kay, and Qutayba Hamid


80 Management of Chronic Asthma 1650
Peter J. Barnes


81 Anti–IgE in Persistent Severe Allergic Asthma 1661
Marc Humbert, Stephen T. Holgate, Howard Fox, and Jean Bousquet


82 Occupational Asthma 1687
Paul Cullinan and Anthony J. Newman Taylor


83 New Drugs for the Treatment of Allergy and Asthma 1712
Trevor T. Hansel, Ed Erin Onn, Min Kon, and Peter J. Barnes


Part 11 Eosinophil–associated Disease and Hypersensitivity Pneumonitis


84 Allergic Bronchopulmonary Aspergillosis 1743
André–Bernard Tonnel, Stéphanie, Pouwels–Frys, and Isabelle Tillie–Leblond


85 Extrinsic Allergic Alveolitis/Hypersensitivity Pneumonitis 1757
Michael C. Zacharisen and Jordan N. Fink


86 Pulmonary Eosinophilia 1779
Jean–François Cordier and Vincent Cottin


87 Hypereosinophilic Syndromes 1802
Hans–Uwe Simon


Part 12 Allergy and the Skin


88 Atopic Dermatitis 1813
Julia D. Proelss and Thomas Bieber


89 Contact Dermatitis 1831
David I. Orton and Carolyn M. Willis


90 Urticaria and Angioedema 1853
Allen P. Kaplan


91 Mastocytosis 1878
Nataliya M. Kushnir–Sukhov, Dean D. Metcalfe, and Jamie A. Robyn


Part 13 Anaphylaxis and Allergy to Food and Drugs


92 Anaphylaxis 1897
M. Rosario Caballero, Stephen J. Lane, and Tak H. Lee


93 Food Allergy and Eosinophilic Gastroenteropathies 1921
Scott H. Sicherer and Hugh A. Sampson


94 Drug Hypersensitivity 1943
Werner J. Pichler


95 Hypersensitivity to Aspirin and other NSAIDs 1966
Andrzej Szczeklik, Ewa NiLankowska–Mogilnicka, and Marek Sanak


96 Insect Sting Allergy 1980
Ulrich R. Müller


Part 14 Prevention of Allergic Disease


97 Prevention of Allergic Disease 1997
Susan L. Prescott and Bengt Björkstén


98 Prevalence of Atopic Disorders in a Developing World: Pitfalls and Opportunities 2020
Maria Yazdanbakhsh, Taniawati Supali, and Laura C. Rodrigues


Index


PRODUCT DETAILS

ISBN-13: 9781444300925
Publisher: John Wiley & Sons Ltd (Wiley–Blackwell)
Publication date: July, 2008
Pages: 2184
Dimensions: 222.00 x 285.00 x 97.50

Subcategories: Immunology, Respiratory Medicine

MEET THE AUTHOR

A Barry Kay, National Heart and Lung Institute, London, UK


Allan P Kaplan, National Allergy and Asthma Centre, South Carolina, USA


Jean Bousquet, Hopital Arnaud dde Villeneuve, Montpellier, France


Patrick G Holt, Telethon Institute for Child Health, Perth, Australia