Autophagy is an emerging biomedical paradigm. It affects all aspects of human health and disease conditions including aging, cancer, immunity and inflammation, Alzheimer's disease, Huntington's disease, Parkinson's disease, diabetes and other metabolic disorders, muscle trophy, and congenital myopathies. It is a fundamental biological process that has an impact on all eukaryotes and is one of the last key biological paradigms remaining to be fully understood.While most reviews focus specifically on individual topics, Autophagy provides a comprehensive review of the current knowledge of autophagy present in the world today. At the same time, the author elaborates on the impact of autophagy on different facets of its domain.
Autophagy - An Introduction; Autophagy as a Fundamental Biological Process; Autophagy as a Biomedical Paradigm; Autophagy as a Programmed Cell Survival vs. Cell Death Process; Autophagy in Aging; Autophagy in Cancer; Autophagy in Neurodegeneration; Autophagy in Muscle Diseases; Autophagy in Metabolic Diseases; Autophagy in Immunity and Inflammation; Autophagy and Informatics; Autophagy for Everyone.